儿童肠白塞病与克罗恩病MR小肠造影影像特征  

MR enterography features of intestinal Behcet disease and Crohn disease in pediatric patients

作　　者：吴朔春[1] 孙雪峰[1] 钟雪梅[2] 仪晓立[1] 陶然[1] 杨梅[1] Wu Shuochun;Sun Xuefeng;Zhong Xuemei;Yi Xiaoli;Tao Ran;Yang Mei(Department of Radiology,Children′s Hospital Affiliated to Capital Institute of Pediatrics,Beijing 100020,China;Department of Gastroenterology,Children′s Hospital Affiliated to Capital Institute of Pediatrics,Beijing 100020,China)

机构地区：[1]首都儿科研究所附属儿童医院放射科,北京100020 [2]首都儿科研究所附属儿童医院消化内科,北京100020

出　　处：《中华放射学杂志》2024年第3期307-312,共6页Chinese Journal of Radiology

摘　　要：目的探讨儿童肠白塞病(BD)及克罗恩病(CD)的MR小肠造影(MRE)影像学特征。方法本研究为横断面研究,回顾性收集2019年1月至2022年10月于首都儿科研究所附属儿童医院确诊的肠BD及CD患儿的临床及MRE影像学资料,其中肠BD患儿17例,男6例、女11例,年龄5~12(8.4±2.6)岁;CD患儿23例,男15例、女8例,年龄7~15(10.2±2.7)岁。观察MRE图像,评估内容包括病变肠管范围,肠壁增厚形式(均匀增厚、偏心增厚)、脂肪抑制T2WI信号、扩散加权成像(DWI)信号、病变肠壁强化方式(均匀强化、分层强化)、肠腔狭窄,肠腔扩张、肠系膜梳状征、肠系膜脂肪纤维化、肠周淋巴结肿大、肠外并发症(包括肛瘘、盆腔积液)。组间MRE征象的比较采用χ2检验或Fisher确切概率法。结果患儿均完成MRE检查,肠道充盈良好,无不良反应。肠BD患儿与CD患儿间病变肠管范围、肠壁增厚形式、DWI信号、肠腔扩张、肠周淋巴结肿大、肛瘘、盆腔积液差异有统计学意义(P<0.05),脂肪抑制T2WI信号、病变肠壁强化方式、肠腔狭窄、肠系膜梳妆征、肠系膜脂肪纤维化差异无统计学意义(P>0.05)。结论MRE安全、有效,肠BD及CD患儿MRE征象间差异有统计学意义。Objective To explore the MR enterography(MRE)features of intestinal Behcet disease(BD)and Crohn disease(CD)in pediatric patients.Methods This study was a cross-sectional study.The BD patients and CD patients were retrospectively enrolled from Children′s Hospital Affiliated to Capital Institute of Pediatrics from January 2019 to October 2022.There were 17 children with intestinal BD,including 6 males and 11 females,aged 5-12(8.4±2.6)years,and 23 children with CD,including 15 males and 8 females,aged 7-15(10.2±2.7)years.The MRE images were observed,and the evaluation contents included the diseased intestine(terminal ileum,ileum+ascending colon,ileum+ascending colon+transverse colon,whole colon),the form of intestinal wall thickening(uniform/eccentric thickening),MRI signal(fat suppression T2WI,DWI),the enhancement mode(uniform/layered enhancement),intestinal stenosis,intestinal dilatation,mesentery comb sign,mesentery fatty fibrosis,lymph node enlargement,and the extraintestinal complication(anal fistula,fluid collection).The comparison of MRE signs between groups was performed using theχ2 test or Fisher exact test.Results All children were completed MRE examination with good intestinal filling,and no adverse reactions.The significant differences were found in the scope of the diseased bowel,the form of intestinal wall thickening,DWI signal,intestinal dilatation,lymph node enlargement,anal fistula and fluid collection between the intestinal BD and CD patients(P<0.05),while no significant differences were found in the fat suppression T2WI signal,enhancement mode of the lesion,intestinal stenosis,mesentery comb sign,and mesentery fatty fibrosis(P>0.05).Conclusion MRE is safe and effective,and there are certain significantly different MRE features between children with intestinal BD and CD.

关 键 词：儿童 磁共振成像 小肠造影 白塞病 CROHN病 

分 类 号：R725.7[医药卫生—儿科]