藏药治疗低氧性肺动脉高压的基础研究进展  

Basic Research Progress of Zang Medicine in Treatment of Hypoxic Pulmonary Hypertension

作　　者：李安平 李怡 许海艳 付家晨 陈俞材 LI Anping;LI Yi;XU Haiyan;FU Jiachen;CHEN Yucai(Department of Pharmacy,School of Traditional Chinese Medicine,Beijing University of Chinese Medicine,Beijing 100029,China;Department of Physiology,School of Traditional Chinese Medicine,Beijing University of Chinese Medicine,Beijing 100029,China)

机构地区：[1]北京中医药大学中药学院药学系,北京100029 [2]北京中医药大学中医学院生理教研室,北京100029

出　　处：《医药导报》2024年第4期545-549,共5页Herald of Medicine

基　　金：国家自然科学基金青年项目(82003983);北京中医药大学“解码中医”揭榜挂帅项目(2022-JYB-JBZR-003);分子药理和药物评价教育部重点实验室开放课题(P202201)。

摘　　要：低氧性肺动脉高压(HPH)是慢性高原病的一种,也是肺心病、高原肺水肿等多种高原病的始动环节,其主要特征是血管持续性收缩和不可逆重构,对高原地区人们的身体健康产生了很大影响。藏药作为民族医药的重要部分,凝聚了藏族人民长期以来与疾病斗争的智慧,因地制宜,对HPH的治疗有独特的优势。该文就HPH的发病机制及单味藏药和藏药复方治疗HPH的研究现状予以综述,以期为HPH的生理、病理研究提供理论依据,同时为藏药的临床应用提供参考。Hypoxic pulmonary hypertension(HPH)is a kind of chronic high-altitude sickness disease,which is also the initiation link of high-altitude sickness such as pneumocardial disease and high-altitude pulmonary edema.Its main features are persistent vasoconstriction and irreversible remodeling of blood vessels.HPH has greatly impacted the health of people in the plateau section.As a typical representative of ethnic medicine,Zang medicine embodies the wisdom of the Zang people in their long-term struggle against diseases.Adapting to local conditions for a long time,Zang medicine has unique advantages in the treatment of HPH.By reviewing the pathogenesis of HPH and the research of single Zang medicine and the complex prescription of Zang medicine in the treatment of HPH,this article aims to provide a theoretical basis for the physiological and pathological research of HPH and to provide a reference for the clinical application of Zang medicine.

关 键 词：藏药 低氧性肺动脉高压 高原病 

分 类 号：R97[医药卫生—药品] R543[医药卫生—药学]