培养基灌装试验在静脉用药集中调配中心的应用及实践探索  

Application and Practical Exploration of Media Fill Test in Pharmacy Intravenous Admixture Services

作　　者：张凡[1] 陆泊宇 白雪[1] 邹羽真[1] 张鑫悦 赵彬[1] 梅丹[1] ZHANG Fan;LU Boyu;BAI Xue;ZOU Yuzhen;ZHANG Xinyue;ZHAO Bin;MEI Dan(Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730,China;Department of Pharmacology and Pharmacy,LKS Faculty of Medicine,The University of Hong Kong,Hong Kong 999077,China)

机构地区：[1]中国医学科学院北京协和医学院北京协和医院,北京100730 [2]香港大学李嘉诚医学院药理及药剂学系,中国香港999077

出　　处：《中国药学杂志》2024年第3期281-284,共4页Chinese Pharmaceutical Journal

摘　　要：目的 针对静脉用药集中调配的无菌操作,我国当前缺少行之有效的人员验证措施,亟需探索无菌操作评估方法。方法 使用美国静脉质量保障(intravenous quality assurance, IVQA)培养基灌装试验套件对我院混合调配人员进行无菌操作验证,初步探索培养基灌装试验在国内静脉用药集中调配中心应用的可行性。结果 培养基灌装试验操作简便,无需苛刻培养条件与检测设备,在2种不同混合调配条件下试验结果不同,可验证人员操作。结论 培养基灌装试验适用于无菌调配操作的人员质控。OBJECTIVE To explore an evaluation method of sterile operation in pharmacy intravenous admixture services(PIVAS).METHODS The US intravenous quality assurance(IVQA)media fill test kit was used to verify the aseptic operation of the mixed dispensing personnel in our hospital,and the feasibility of applying the media fill test in the PIVAS was preliminarily explored.RESULTS The media fill test was easy to operate without harsh culture conditions and testing equipment.The test results were different under two different mixing conditions,which can verify the operation of personnel.CONCLUSION The media fill test is applicable to the quality control of personnel in sterile dispensing operations.

关 键 词：培养基灌装试验 无菌操作 质量控制 静脉用药集中调配中心 

分 类 号：R952[医药卫生—药学]