穴位贴敷联合艾灸治疗慢性浅表性胃炎疗效观察及对胃肠激素水平的影响  

Curative Effect of Point Application Combined with Moxibustion for Chronic Superfi⁃cial Gastritis and Its Effect on Gastrointestinal Hormones

作　　者：赵浩靖 林雪冬 黄小燕 赵薪薪 ZHAO Haojing;LIN Xuedong;HUANG Xiaoyan;ZHAO Xinxin(Department of Gastroenterology,Wenzhou Traditional Chinese Medicine Hospital,Wenzhou Zhejiang 325000,China;Department of Nephropathy,Wenzhou Traditional Chinese Medicine Hospital,Wenzhou Zhejiang 325000,China)

机构地区：[1]温州市中医院消化内科,浙江温州325000 [2]温州市中医院肾病科,浙江温州325000

出　　处：《新中医》2024年第4期160-163,共4页New Chinese Medicine

摘　　要：目的:观察穴位贴敷联合艾灸治疗慢性浅表性胃炎(CSG)的临床疗效以及对胃肠激素水平的影响。方法:选取100例CSG患者,按随机数字表法分为观察组和对照组各50例。对照组采用奥美拉唑肠溶胶囊联合艾灸治疗,观察组在对照组基础上加用穴位敷贴治疗。比较2组临床疗效、中医证候评分、胃肠激素[胃泌素(GAS)、生长抑素(SS)、胃动素(MLT)]水平以及不良反应。结果:观察组总有效率为86.00%,对照组为68.00%,2组比较,差异有统计学意义(P<0.05)。治疗前,2组胃痛、饮食减少、恶心呕吐、善太息、嗳气吞酸等中医证候评分比较,差异均无统计学意义(P>0.05);治疗后,2组上述各项评分均较治疗前降低(P<0.05),且观察组各项评分均低于对照组(P<0.05)。治疗前,2组血清GAS、SS、MLT水平比较,差异无统计学意义(P>0.05)。治疗后,2组GAS水平均较治疗前降低(P<0.05),SS、MLT水平均较治疗前升高(P<0.05);且观察组GAS水平低于对照组(P<0.05),SS、MLT水平高于对照组(P<0.05)。治疗过程中,2组均未出现明显不良反应。结论:穴位贴敷联合艾灸治疗CSG疗效确切,可有效改善中医证候及胃肠激素水平,且治疗安全性良好。Objective:To observe the clinical effect of point application combined with moxibustion for chronic superficial gastritis(CSG)and its effect on gastrointestinal hormones.Methods:A total of 100 cases of CSG patients were selected and divided into the observation group and the control group according to the random number table method,with 50 cases in each group.The control group was treated with Omeprazole Enteric-Coated Capsules combined with moxibustion,and the observation group was treated with acupoint application on the basis of the control group.Clinical effects,traditional Chinese medicine(TCM)syndrome scores,the levels of gastrointestinal hormones[gastrin(GAS),somatostatin(SS),and motilin(MLT)],and adverse reactions were compared between the two groups.Results:The total effective rate was 86.00%in the observation group and 68.00%in the control group,the difference being significant(P<0.05).Before treatment,there was no significant difference being found in the comparison of TCM syndrome scores of stomachache,reduced food intake,nausea and vomiting,sighing,belching,and acid swallowing between the two groups(P>0.05);after treatment,the above scores in the two groups were decreased when compared with those before treatment(P<0.05),and each score in the observation group was lower than that in the control group(P<0.05).Before treatment,there was no significant difference being found in the comparison of the levels of GAS,SS,and MLT in serum between the two groups(P>0.05).After treatment,GAS levels in the two groups were decreased when compared with those before treatment(P<0.05),and the levels of SS and MLT were increased when compared with those before treatment(P<0.05);GAS level in the observation group was lower than that in the control group(P<0.05),and the levels of SS and MLT in the observation group were higher than those in the control group(P<0.05).During treatment,there were no obvious adverse reactions in the two groups.Conclusion:Point application combined with moxibustion has a definite curative ef

关 键 词：慢性浅表性胃炎 奥美拉唑肠溶胶囊 穴位贴敷 艾灸 胃泌素 生长抑素 胃动素 

分 类 号：R5743.31[医药卫生—消化系统]