超微血流显像技术在评估肠道克罗恩病病变活动性中的应用价值  

Application Value of Ultra-micro Blood Flow Imaging Technology in Evaluating the Activity of Intestinal Crohn's Disease

作　　者：郑佩玲 田钦南 ZHENG Pei-ling;TIAN Qin-nan(Department of Medical Ultrasound,Jiangmen Central Hospital,Guangdong 529000,China)

机构地区：[1]江门市中心医院医学超声科,广东529000

出　　处：《影像技术》2024年第2期4-8,共5页Image Technology

基　　金：2022年江门市科技计划项目(2022YL01045)。

摘　　要：目的:探讨超微血流显像技术(SMI)在评估肠道克罗恩病(CD)病变活动性方面的应用价值。方法:选取2022年4月-2023年8月在江门市中心医院消化内科及儿内科门诊或住院治疗确诊为克罗恩病的患者60例。根据随机数字表法将其随机分为参照组和对照组各30例。参照组患者接受SMI技术评估病变肠管肠壁的血流情况,对照组患者接受PDI技术评估病变肠管肠壁的血流情况。结果:参照组中CD病变肠管形态分级显著高于对照组(t=4.762,P<0.05),病变肠管大小显著小于参照组(t=5.192,P<0.05)。参照组肠壁血流灌注度评分和肠管完整性评分方面高于对照组(χ^(2)=4.702,3.852,P<0.05),在血流峰值速度和血流体积流量方面,参照组也高于对照组(t=4.376,5.376,P<0.05)。参照组的病变肠管活动程度(CDAI评分)和炎症程度(SES-CD评分)低于对照组(t=4.269,4.059,P<0.05)。参照组的肠道血管密度显著高于对照组(t=12.127,P<0.05)。结论:本研究结果表明,在评估肠道克罗恩病病变活动性方面,超微血流显像技术(SMI)比能量多普勒技术(PDI)更为准确和可靠,能够提供更具有临床应用价值的病变活动性评估。Objective:The purpose of this study is to explore the application value of super microvas⁃cular imaging,(SMI)in evaluating the activity of intestinal Crohn's disease(CD).Methods:From April 2022 to August 2023,60 patients diagnosed as Crohn's disease were selected from outpatient or inpatient treatment in the Department of Gastroenterology and Pediatrics of Jiangmen Central Hospital.According to the random number table method,they were randomly divided into reference group and control group with 30 cases in each group.Patients in the reference group received SMI technique to evaluate the blood flow of the diseased intestinal wall,while patients in the control group received PDI technique to evaluate the blood flow of the diseased intestinal wall.Results:In the reference group,the intestinal morphology of CD lesions was significantly higher than that in the control group(t=4.762,P<0.05),and the intestinal size of CD lesions was significantly smaller than that in the reference group(t=5.192,P<0.05).The scores of intestinal wall blood perfusion and intestinal integrity in the reference group were higher than those in the control group(χ^(2)=4.702,3.852,P<0.05),and the peak velocity and volume flow of blood in the refer⁃ence group were also higher than those in the control group(t=4.376,5.376,P<0.05).The degree of intes⁃tinal activity(CDAI score)and inflammation(SES-CD score)in the reference group were lower than those in the control group(t=4.269,4.059,P<0.05).The intestinal vascular density in the reference group was significantly higher than that in the control group(t=12.127,P<0.05).Conclusion:The results of this study show that the super microvascular imaging(SMI)is more accurate and reliable than the power Dop⁃pler imaging(PDI)in evaluating the pathological activity of intestinal Crohn's disease,and it can provide more clinical application value for evaluating the pathological activity.

关 键 词：超微血流显像技术 能量多普勒技术 克罗恩病 肠道病变 

分 类 号：R445.1[医药卫生—影像医学与核医学]