白竭散对肛周脓肿术后创面愈合的疗效观察  

Clinical Effect of Baijie Powder on Wound Healing after Perianal Abscess Surgery

作　　者：唐昆[1] 陈力 李明[1] 李敏 朱竞[2] TANG Kun;CHEN Li;LI Ming;LI Min;ZHU Jing(The First Affiliated Hospital of Anhui University of Chinese Medicine,Anhui Hefei230031,China;Hefei First People’s Hospital,Anhui Hefei230000,China)

机构地区：[1]安徽中医药大学第一附属医院,安徽合肥230031 [2]合肥市第一人民医院,安徽合肥230000

出　　处：《安徽中医药大学学报》2024年第2期24-27,共4页Journal of Anhui University of Chinese Medicine

基　　金：安徽省青年领军后备人才支持项目(皖发〔2020〕11号)。

摘　　要：目的观察白竭散对肛周脓肿术后创面愈合的作用。方法将60例患者随机分为治疗组和对照组,每组30例。两组均采用痔瘘洗剂坐浴和复方黄柏液涂剂清洗创面,治疗组在此基础上采用白竭散外敷创面。比较两组临床症状(肛门疼痛、水肿程度、创面分泌物)评分、肉芽生长情况评分、创面愈合率、创面组织细胞(毛细血管数、成纤维细胞数、巨噬细胞比)及疗效。结果术后3 d,两组创面指标(肛门疼痛、水肿程度、创面分泌物)评分及创面组织细胞(毛细血管数、成纤维细胞数、巨噬细胞比)比较,差异均无统计学意义(P>0.05)。术后7、14 d,治疗组创面指标(肛门疼痛、水肿程度、创面分泌物)评分、创面组织细胞(毛细血管数、成纤维细胞数、巨噬细胞比)均显著大于对照组(P<0.05)。治疗组疗效优于对照组(P<0.05)。结论白竭散促进肛周脓肿术后创面愈合效果显著,可缓解患者术后临床症状,促进术后肛门功能的恢复。Objective To investigate the clinical effect of Baijie Powder on wound healing after perianal abscess surgery.Methods A total of 60 patients were randomly divided into treatment group and control group,with 30 patients in each group.The patients in the control group received sitz bath with hemorrhoids-fistula lotion and wound cleaning with Compound Huangbai Liquid,and those in the treatment group received Baijie Powder in addition to the treatment in the control group.The two groups were compared in terms of clinical symptom(anal pain,degree of edema,and wound secretions)scores,granulation growth score,wound healing rate,wound tissue cells(number of capillaries,number of fibroblasts,and percentage of macrophages),and clinical outcome.Results There were no significant differences in wound indicators and wound tissue cells between the two groups on day 3 after surgery(P>0.05).On days 7 and 14 after surgery,compared with the control group,the treatment group had significantly higher clinical symptom(anal pain,degree of edema,and wound secretions)scores and indicators of wound tissue cells(number of capillaries,number of fibroblasts,and percentage of macrophages)(P<0.05).The treatment group had a significantly better clinical outcome than the control group(P<0.05).Conclusion Baijie Powder has a marked clinical effect in promoting wound healing after perianal abscess surgery and can alleviate postoperative clinical symptoms and promote postoperative recovery of anal function.

关 键 词：白竭散 创面愈合 肛周脓肿 

分 类 号：R657.15[医药卫生—外科学]