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作 者:中华预防医学会劳动卫生与职业病分会职业性肺部疾病学组 毛翎 彭莉君 王焕强[4] 李宝平 MAO Ling
机构地区:[1]不详 [2]同济大学附属上海市肺科医院 [3]四川大学华西第四医院 [4]中国疾病预防控制中心职业卫生所 [5]应急总医院
出 处:《环境与职业医学》2024年第1期1-21,共21页Journal of Environmental and Occupational Medicine
摘 要:尘肺病是我国最严重的职业病,其防治措施一直受到广泛关注。尘肺病是肺组织结构破坏、肺功能受损的间质纤维化性疾病。汉防己甲素(粉防己碱)和尼达尼布有明确延缓尘肺病纤维化进展的作用,因此应该重视尘肺病尤其快进型矽肺的抗纤维化治疗。全面健康管理,早期开展抗纤维化治疗,积极预防和治疗肺结核等并发症及合并症,定期康复治疗和训练,尘肺病患者基本可以保持正常的生活质量和相对健全的社会活动能力。Pneumoconiosis is the most serious occupational disease in China,and the prevention and treatment of pneumoconiosis attracts extensive social concerns.As a pulmonary interstitial fibrotic disease,pneumoconiosis is featured by disrupted lung tissue structure and impaired lung function.With available evidence on tetrandrine and nintedanib demonstrably retarding the progression of pneumoconiosis fibrosis,antifibrotic treatment of pneumoconiosis,especially rapidly progressive silicosis,should be emphasized.Pneumoconiosis patients could maintain an average level of quality of life and capabilities in social activities through comprehensive health management,early initiation of antifibrotic treatment,active prevention and treatment of pulmonary tuberculosis and other complications and comorbidities,as well as regular rehabilitation treatment and training.
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