慢性阻塞性肺疾病合并胃食管反流症的中西医研究进展  

Research Progress of Traditional Chinese and Western Medicine on Chronic Obstructive Pulmonary Disease with Gastroesophageal Reflux Disease

作　　者：李景泽 庞立健[2] 臧凝子[2] 王琳琳[2] 邹吉宇 张馨心 吕晓东[1] LI Jingze;PANG Lijian;ZANG Ningzi;WANG Linlin;ZOU Jiyu;ZHANG Xinxin;LYU Xiaodong(Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China;Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110032,Liaoning,China)

机构地区：[1]辽宁中医药大学,辽宁沈阳110847 [2]辽宁中医药大学附属医院,辽宁沈阳110032

出　　处：《辽宁中医药大学学报》2024年第4期96-100,共5页Journal of Liaoning University of Traditional Chinese Medicine

基　　金：国家自然科学基金青年科学基金资助项目(82104804);辽宁省教育厅项目(LJKZ0880)。

摘　　要：慢性阻塞性肺疾病(COPD)是严重威胁人类生命和财产安全的一种慢性、渐进的呼吸疾病,其发病和病死率极高。胃食管反流(GERD)是常见的消化道疾病。愈来愈多的医学临床研究表明,COPD合并GERD的患病率远高过正常人,由于临床一些表现相似,相关的病理学体制尚不清楚,很有可能会造成错诊,失去治疗的最佳时间,造成不必要的经济损失。目前主流观点有反流学说和反射学说,以药物治疗、手术治疗及改善生活方式为主要治疗方式;传统医学将其定义为“肺胀”合并“嘈杂”“吐酸”或“痞满”,主要责之于肺胃虚损,气郁痰阻之本虚标实证,以补益肺脾胃气、降逆止咳化痰为主要的中医治法。在过去的十年里,两者之间的关系越来越受到关注。文章总结了中西医发表的有关COPD和GERD的研究进展,为今后治疗COPD和GERD的研究提供理论依据。Chronic obstructive pulmonary disease(COPD)is a chronic,progressive respiratory disease that seriously threatens human life and property,with extremely high morbidity and mortality.Gastroesophageal reflux disease(GERD)is a common digestive tract disease.More and more medical clinical studies have shown that the prevalence of COPD combined with GERD is much higher than that of normal people,due to some similar clinical manifestations,the relevant pathological system is not clear,which is likely to cause misdiagnosis,lose the best time for treatment,and cause unnecessary economic losses.At present,the mainstream views include reflux theory and reflex theory,with drug treatment,surgical treatment and lifestyle improvement as the main treatment methods;Traditional medicine defines it as“lung distension”combined with“noisy”“acid vomiting”or“ruffian”,which is mainly responsiblefor lung and stomach deficiency,and the basic evidence of Qi depression and phlegm obstruction,so as toreplenish the lungs,spleen and stomach Qi,reduce cough and reduce phlegm as the main Chinese medicinetreatment. Over the past decade,the relationship between the two has gained increasing attention. Thisarticle summarizes the research progress on COPD and GERD published by traditional Chinese and Westernmedicine,and provides a theoretical basis for future research on the treatment of COPD and GERD.

关 键 词：慢性阻塞性肺疾病 胃食管反流 合并症 

分 类 号：R259[医药卫生—中西医结合]