针刺募穴联合口服美沙拉嗪治疗溃疡性结肠炎的临床观察  

Clinical Observation of Treating Ulcerative Colitis with Acupuncture at Front Mu Points Combined with Oral Mesalazine

作　　者：李春玲 李玲华[1] 韩旭 杨洁[1] 张衡[1] LI Chunling;LI Linghua;HAN Xu;YANG Jie;ZHANG Heng(Dept.of Anorectal,Kunming Municipal Hospital of Traditional Chinese Medicine,Kunming Yunnan 650500,China)

机构地区：[1]昆明市中医医院肛肠科,云南昆明650500

出　　处：《昆明医科大学学报》2024年第3期72-78,共7页Journal of Kunming Medical University

基　　金：云南省科技厅科技计划基金资助项目(202101AZ070001-125);昆明市卫生健康委员会卫生科研课题(2022-04-01-007)。

摘　　要：目的观察针刺募穴治疗溃疡性结肠炎的临床疗效。方法收集昆明市中医医院2022年8月至2023年6月收治的溃疡性结肠炎患者60例。随机数字表法,分为对照组、联合组各30例,治疗方法为连续8周予对照组口服美沙拉嗪,联合组美沙拉嗪口服结合针刺募穴。从治疗前后临床疗效、肠镜结果评分(the baron score,Baron)、结肠粘膜愈合评分(colonic mucosal healingscore,Geboes)3个方面进行比较,并随访3月,计算联合组、对照组疾病复发率。结果临床疗效联合组高于对照组(P<0.05),总有效率分别为93.33%、67.67%,治疗后,疾病活动指数、Baron评分、Geboes评分较治疗前下降(P<0.05),联合组治疗后疾病活动指数、Baron评分、Geboes评分比对照组低(P<0.05)。比较治疗后3月的疾病复发率,发现联合组低于对照组。结论针刺募穴明显改善溃疡性结肠炎临床症状,相较于对照组患者,降低了复发机率,安全可靠,未见严重不良反应。Objective To observe the clinical efficacy of acupuncture at Front Mu point in the treatment of ulcerative colitis.Methods Sixty patients with ulcerative colitis treated at the Traditional Chinese Medicine Hospital in Kunming from August 2022 to June 2023 were collected.Using a random number table method,30 cases were assigned to each of the control group and the combined group.The treatment method involved administering oral mesalazine to the control group for a continuous period of 8 weeks,while the combined group received both oral mesalazine and acupuncture at front Mu points.The clinical efficacy,colonoscopy results score(Baron score),and colonic mucosal healing score(Geboes)before and after treatment were compared.Follow-up was conducted at 3 months to calculate the recurrence rate in the combination and control groups.Results The total effective rate in the combination group was higher than that in the control group(P<0.05),with rates of 93.33%and 67.67%,respectively.After treatment,the disease activity index,Baron score,and Geboes score decreased compared to before treatment(P<0.05),and the combination group had a lower disease activity index,Baron score,and Geboes score than the control group after treatment(P<0.05).Comparing the recurrence rates at 3 months posttreatment,the combination group was lower than the control group.Conclusion Acupuncture at Front Mu Point can significantly improve the clinical symptoms of ulcerative colitis,reduce the recurrence rate compared to patients in the control group,and is safe and reliable without serious adverse reactions.

关 键 词：溃疡性结肠炎 美沙拉嗪 募穴 疗效 复发率 

分 类 号：R266[医药卫生—中医外科学]