生物活性玻璃在骨及软组织修复的研究进展  

Research progress of bioactive glass in bone and soft tissue repair

作　　者：吴煌超 孙劲[1] 黄俊涛 WU Huangchao;SUN Jin;HUANG Juntao(Department of Orthopaedics,the Third Clinical Hospital of Three Gorges University,Gezhouba Central Hospital,Yichang 443002,China;不详)

机构地区：[1]三峡大学第三临床医学院国药葛洲坝中心医院骨科,湖北宜昌443002 [2]三峡大学第三临床医学院国药葛洲坝中心医院中医科,湖北宜昌443002

出　　处：《实用医学杂志》2024年第6期867-869,876,共4页The Journal of Practical Medicine

基　　金：湖北省教育厅科学研究计划项目(编号:B2022029)。

摘　　要：生物活性玻璃(bioactive glass,BG)因其相容性、生物活性和形成结晶羟基磷灰石层的能力而被用作骨及软组织修复材料的候选。本文介绍了BG离子释放机制,探讨了硼硅酸盐生物活性玻璃(borosilicate bioactive glass, BBG)在骨和软组织修复中的应用,并就BBG在骨水泥、支架、水凝胶和纤维研究应用中的潜力及所面临的临床转化挑战展开综述。Bioactive glass(BG)has been used as a candidate for bone and soft tissue repair materials because of its compatibility,bioactivity and ability to form a crystalline hydroxyapatite layer.This paper introduces the mechanism of BG ion release,discusses the application of borosilicate bioactive glass(BBG)in bone and soft tissue repair,and provides an overview of the potential and clinical translational challenges faced by BBG in bone cement,scaffold,hydrogel,and fiber research applications.

关 键 词：生物活性玻璃 骨组织 软组织 修复 

分 类 号：R683[医药卫生—骨科学]