安全性视角下基本药物制度评价模型构建及效果评价  

Construction and Effectiveness Evaluation of the Evaluation Model of Essential Drug System from the Perspective of Safety

作　　者：唐婉 陈红斗 张子歆 尤正仪 林彦全 TANG Wan;CHEN Hongdou;ZHANG Zixin;YOU Zhengyi;LIN Yanquan(Suqian Hospital Affiliated to Xuzhou Medical University·Suqian Hospital of Nanjing Drum Tower Hospital Group,Suqian,Jiangsu,China 223800;Xuzhou Medical University,Xuzhou,Jiangsu,China 221000)

机构地区：[1]徐州医科大学附属宿迁医院·南京鼓楼医院集团宿迁医院,江苏宿迁223800 [2]徐州医科大学,江苏徐州221000

出　　处：《中国药业》2024年第7期13-16,共4页China Pharmaceuticals

基　　金：江苏省宿迁市第五期“333高层次人才培养工程”科研项目[BRA2020234];江苏省药学会-天晴医院药学基金科研课题[Q202043]。

摘　　要：目的构建安全性视角下基本药物制度评价模型,为基本药物安全性管理提供参考。方法通过德尔菲法和层次分析法确定各级指标和权重,构建安全性评价模型。利用中国上市药品目录集、《中国药典》等收集基本药物(2018年)安全性指标数据。运用李克特量表法对实证数据进行评分,将评分值输入构建的模型中,获得安全性视角下基本药物制度的效果评价分值。结果构建模型的5个一级指标(准则层)的权重分别为0.261,0.189,0.431,0.075,0.083,10个二级指标(指标层)的权重分别为0.504,0.496,0.433,0.567,0.429,0.571,1.000,0.252,0.551,0.196。运用该模型对基本药物进行实证评估,综合评价总得分为3.684分,综合评价为73.68%。结论构建的模型稳定可靠、具有可行性,能全面反映基本药物的安全性,现行基本药物的安全管理需进一步完善。Objective To construct an evaluation model of the essential drug system from the perspective of safety,and to provide a reference for the safety management of essential drugs.Methods The Delphi method combined with the Analytic Hierarchy Process(AHP)was used to determine the indicators and weights at all levels of the model,and to construct the safety evaluation model.The safety index data of essential drugs(2018)in China were collected by using the China Listed Drug Catalogue and the Chinese Pharmacopoeia.The empirical data were scored by the Likert scale method,and the rating value was input into the model to obtain the evaluation scores of the implementation effect of the national essential drugs system from the perspective of safety.Results The weights of the five first-level indicators(criterion layer)of the constructed evaluation model were 0.261,0.189,0.431,0.075,and 0.083,respectively.The weights of the ten second-level indicators(index layer)of the constructed evaluation model were 0.504,0.496,0.433,0.567,0.429,0.571,1.000,0.252,0.551,and 0.196,respectively.The model was used to empirically evaluate the safety of the essential drugs,with a total score of 3.684 points and a comprehensive evaluation of 73.68%.Conclusion The constructed model is stable,reliable,and feasible,which can comprehensively reflect the safety of essential drugs.The current safety management of essential drugs needs to be further improved.

关 键 词：国家基本药物制度 安全性 评价指标体系 层次分析法 德尔菲法 

分 类 号：R95[医药卫生—药学]