氮杂环卡宾催化的五氟苯基硫醚的合成  

N-Heterocyclic Carbene-Catalyzed Synthesis of Pentafluorophenyl Sulfides

作　　者：夏登鹏 罗锦昀 何林[1] 蔡志华 杜广芬[1] Xia Dengpeng;Luo Jinyun;He Lin;Cai Zhihua;Du Guangfen(School of Chemistry and Chemical Engineering,Shihezi University,Shihezi,Xinjiang 832000)

机构地区：[1]石河子大学化学化工学院,新疆石河子832000

出　　处：《有机化学》2024年第2期622-630,共9页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(No.21662029);石河子大学国际合作(No.GJHZ202204)资助项目.

摘　　要：利用氮杂环卡宾催化剂的强Lewis碱性,发展了一种构建C(sp^(2))—S键的有效方法.稳定的氮杂环卡宾1,3-双(2,6-二异丙基苯基)咪唑-2-亚基可以对五氟苯基三甲基硅烷的C—Si键进行有效活化,进而引发与硫代磺酸酯的亲核取代反应,以34%~98%的产率生成五氟苯基硫醚产物.An efficient method for the construction of C(sp^(2))—S bond has been developed.The stable N-heterocyclic carbene 1,3-bis(2,6-dissopropylphenyl)-imidazole-2-ylidene can activate the C—Si bond of pentafluorophenyl trimethylsilicon effectively to initiate the nucleophilic substitution reaction with thiosulfonic ester,producing pentafluorophenyl sulfide products in 34%~98%yields.

关 键 词：氮杂环卡宾 C—S键 五氟苯基硫醚 

分 类 号：O625.72[理学—有机化学]