7576张含丹参-当归药对的门诊中药饮片处方回顾性分析  

Retrospective Analysis of 7576 Outpatient Prescriptions of Traditional Chinese Medicine Decoction Pieces Containing Salviae Miltiorrhizae Radix et Rhizoma-Angelicae Sinensis Radix Herb Pairs

作　　者：王红[1,2] 蒋征 刘玲[1,2] 孙霞[1,2] 崔永伟 WANG Hong;JIANG Zheng;LIU Ling;SUN Xia;CUI Yongwei(Dept.of Pharmacy,the South Part of Jiangsu Province Hospital of Integrated Traditional Chinese and Western Medicine/Nanjing Lishui District Hospital of Traditional Chinese Medicine,Nanjing 211200,China;Dept.of Pharmacy,Nanjing Lishui District Hospital of Traditional Chinese Medicine,Affiliated to Medical College of Yangzhou University,Nanjing 211200,China;College of Pharmacy,Nanjing University of Chinese Medicine,Nanjing 210046,China)

机构地区：[1]江苏省中西医结合医院南部院区/南京市溧水区中医院药学部,南京211200 [2]扬州大学医学院附属南京市溧水区中医院药学部,南京211200 [3]南京中医药大学药学院,南京210046

出　　处：《中国医院用药评价与分析》2024年第3期352-356,361,共6页Evaluation and Analysis of Drug-use in Hospitals of China

基　　金：江苏省道地药材生态种植及质量保障项目(2022);南京市中医药青年人才培养计划项目(No.ZYQ20059);南京药学会-常州四药医院药学科研基金项目(No.2019YX023);南京市中医药科技专项中医药青年人才项目(No.ZYQN202209)。

摘　　要：目的:了解江苏省中西医结合医院南部院区/南京市溧水区中医院(以下简称“该院”)含丹参-当归药对的门诊中药饮片处方情况,探究该药对的临床配伍应用规律,为该药对的合理使用提供参考。方法:采用回顾性分析方法,统计2020—2022年该院使用丹参-当归药对的7576张门诊中药饮片处方,对患者的性别、年龄、处方药味数、金额、疗程、涉及科室及病症、使用剂量、常用的配伍比例及配伍饮片等相关内容进行统计分析。结果:7576张含丹参-当归药对的门诊中药饮片处方中,女性患者处方数约为男性患者处方数的3.21倍(5776张vs.1800张),>30~40岁患者居多。单张处方的中药饮片味数多集中在16~20味,开具的疗程均<30 d。丹参的使用剂量为《中华人民共和国药典》规定的10~15 g的处方有6490张,占85.67%;当归的使用剂量为《中华人民共和国药典》规定的6~12 g的处方有6608张,占87.22%。处方数排序居前3位的科室依次为国医堂、妇科及脑病科,治疗的病证以冲任失调、心脾两虚及气滞血瘀证为主。单张处方中丹参用量大于等于当归用量,丹参与当归的配伍比例以1∶1为多,高频配伍饮片为茯苓、川芎、炒白芍。结论:基于处方用药分析,该院含丹参-当归药对的门诊中药饮片处方基本合理,为丹参-当归药对的使用剂量范围及配伍规律研究提供了数据支持,有利于促进临床合理用药。OBJECTIVE:To investigate the outpatient prescriptions of traditional Chinese medicine decoction pieces containing Salviae Miltiorrhizae Radix et Rhizoma-Angelicae Sinensis Radix herb pairs in the South Part of Jiangsu Province Hospital of Integrated Traditional Chinese and Western Medicine/Nanjing Lishui District Hospital of Traditional Chinese Medicine(hereinafter referred to as“the hospital”),and to probe into the clinical compatibility laws of the herb pair,so as to provide reference for rational drug use.METHODS:Retrospective analysis was performed on 7576 outpatient prescriptions of traditional Chinese medicine decoction pieces containing Salviae Miltiorrhizae Radix et Rhizoma-Angelicae Sinensis Radix herb pairs from 2020 to 2022.Gender,age,number of herbs per prescription,consumption sum,treatment course,involved departments and disease,dosage,common compatibility ratios and compatible decoction pieces were statistically analyzed.RESULTS:Among the 7576 outpatient prescriptions of traditional Chinese medicine decoction pieces containing Salviae Miltiorrhizae Radix et Rhizoma-Angelicae Sinensis Radix herb pairs,the number of prescriptions in female patients was 3.21 times that in male patients(5776 prescriptions vs.1800 prescriptions),and the majority of patients were>30 to 40 years old.The number of herbs per prescription was mostly from 16 to 20.The treatment course was less than 30 days.Salviae Miltiorrhizae Radix et Rhizoma was prescribed at 10 to 15 g per day according to the Chinese Pharmacopoeia in 6490 prescriptions,accounting for 85.67%.Angelicae Sinensis Radix was prescribed at 6 to 12 g per day according to the Chinese Pharmacopoeia in 6608 prescriptions,according for 87.22%.The top three departments in terms of prescription count were Guoyitang,gynecology and neurology,the main treated syndromes were Chong Ren dysfunction,dual deficiency of heart and spleen,and Qi stagnation with blood stasis.The amount of Salviae Miltiorrhizae Radix et Rhizoma was equal to or greater than that of Angelicae Si

关 键 词：丹参 当归 药对 处方分析 合理用药 

分 类 号：R932[医药卫生—生药学] R969.3[医药卫生—药学]