心房颤动患者射频消融术前后焦虑、抑郁及证候要素分析  

Anxiety,Depression and TCM Syndrome Element in Patients withAtrial Fibrillation Before and After Radiofrequency Ablation

作　　者：刘伟 李星星 林泉 范宗静[2] 崔杰[2] 胡继强[2] 吴旸[2] LIU Wei;LI Xingxing;LIN Quan;FAN Zongjing;CUI Jie;HU Jiqiang;WU Yang(The Second Clinical Medical College of Beijing University of Chinese Medicine,Beijing China 100078;Dongfang Hospital,Beijing University of Chinese Medicine,Beijing China 100078)

机构地区：[1]北京中医药大学第二临床医学院,北京100078 [2]北京中医药大学东方医院,北京100078

出　　处：《中医学报》2024年第4期865-869,共5页Acta Chinese Medicine

基　　金：国家自然科学基金项目(81573900);中央高校基本科研业务费专项资金项目(2022-JYB-XJSJJ-073)。

摘　　要：目的:分析心房颤动患者射频消融术前后焦虑、抑郁状态的演变及证候要素的特点,为心房颤动患者射频消融术后的中医药治疗提供依据。方法:收集90例心房颤动且接受射频消融术治疗患者术前、术后1周及术后1个月时相关指标,并采用SPSS 25.0软件处理数据。结果:(1)焦虑和抑郁:术后1周,焦虑患者数量(36例)略高于术前(32例),差异无统计学意义(P>0.05);术后1个月,焦虑患者数量(19例)明显低于术前(32例)及术后1周(36例),差异有统计学意义(P<0.05)。术后1周,抑郁患者数量(37例)高于术前(21例);术后1个月,抑郁患者数量(14例)低于术后1周,差异均有统计学意义(P<0.05);术后1个月,抑郁患者数量(14例)略低于术前(21例),差异无统计学意义(P>0.05)。(2)焦虑和抑郁证素分布及演变:术前,焦虑患者中气虚证(62.5%)、阴虚证(53.1%)较多,其次为气滞证(25.0%),术后1周、术后1个月,血瘀证比例(44.4%、47.4%)高于气滞证(27.8%、26.3%);术前,抑郁患者中气虚证(47.6%)、气滞证(42.9%)、血瘀证(42.9%)较多,术后1周、术后1个月,血瘀证比例(70.3%、71.4%)高于气虚证(51.4%、42.9%)、气滞证(40.5%、42.9%)。结论:(1)射频消融术对于心房颤动患者焦虑、抑郁状态具有一定影响。焦虑状态术后1周时加重不明显,术后1个月时明显减轻;抑郁状态术后1周时明显加重,术后1个月时恢复到术前水平。(2)焦虑患者术前的中医证素主要是气虚、阴虚、气滞,抑郁患者则为气虚、气滞、血瘀,二者术后血瘀证均明显增加。Objective:To analyze the change of anxiety and depression as well as the characteristics of TCM syndrome elements in patients with atrial fibrillation before and after radiofrequency ablation,so as to provide a basis for TCM treatment in patients with atrial fibrillation after radiofrequency ablation.Methods:Relevant indicators that before radiofrequency ablation surgery,1 week and 1 month after radiofrequency ablation surgery were collected from 90 patients with atrial fibrillation,and the data was processed using SPSS 25.0 software.Results:(1)Anxiety and depression:One week after the surgery,the number of anxiety patients(36 cases)was slightly higher than that before the surgery(32 cases),the difference was not statistically significant(P>0.05);One month after the surgery,the number of anxiety patients(19 cases)was significantly lower than that before the surgery(32 cases)and one week after the surgery(36 cases),and the difference was statistically significant(P<0.05).One week after the surgery,the number of patients with depression(37 cases)was higher than that before the surgery(21 cases);One month after the surgery,the number of patients with depression(14 cases)was lower than that of one week after the surgery,and the differences were statistically significant(P<0.05);One month after the surgery,the number of patients with depression(14 cases)was slightly lower than that before the surgery(21 cases),and the difference was not statistically significant(P>0.05).(2)Distribution and changes of anxiety and depression syndrome elements:Before the surgery,there were more Qi deficiency syndrome(62.5%)and Yin deficiency syndrome(53.1%)in anxiety patients,followed by Qi stagnation syndrome(25.0%).One week and one month after the surgery,the proportion of blood stasis syndrome(44.4%,47.4%)was higher than that of Qi stagnation syndrome(27.8%,26.3%);Before the surgery,there were more Qi deficiency syndrome(47.6%),Qi stagnation syndrome(42.9%)and blood stasis syndrome(42.9%)in patients with depression.One week and one mo

关 键 词：焦虑 抑郁 射频消融术 心房颤动 证候要素 

分 类 号：R256.22[医药卫生—中医内科学]