2017—2022年贵州省肺结核患者治疗转归及影响因素分析  

Treatment outcomes and influencing factors in pulmonary tuberculosis patients in Guizhou,2017-2022

作　　者：马晓雪 王大福 陈再平[1] 周建 陈璞[1] 陈美 刘益宁 李进岚[1] MA Xiao-xue;WANG Da-fu;CHEN Zai-ping;ZHOU Jian;CHEN Pu;CHEN Mei;LIU Yi-ning;LI Jin-lan(Institute of Tuberculosis Control,Guizhou Center for Disease Control and Prevention,Guiyang,Guizhou 550004,China;不详)

机构地区：[1]贵州省疾病预防控制中心结防所,贵州贵阳550004 [2]贵州医科大学公共卫生与健康学院

出　　处：《现代预防医学》2024年第6期1129-1134,共6页Modern Preventive Medicine

基　　金：贵州省发改委省级基本建设前期工作项目(2020-181-131)。

摘　　要：目的分析贵州省肺结核患者的治疗结局及影响因素,为完善肺结核防控策略提供依据。方法从结核病信息管理系统导出2017—2022年贵州省肺结核患者个案,用率(%)描述治疗成功的分布特征,采用χ^(2)检验和二分类logistic回归模型分析其影响因素。结果2017—2022年贵州省肺结核患者年均登记率为97.27/10万,呈逐年下降趋势(趋势χ^(2)=2230.684,P<0.001)。同期患者治疗成功率为92.89%,呈上升趋势(趋势χ^(2)=51.800,P<0.001)。男性、≥60岁年龄组、毕节市患者的治疗成功率较低。影响因素分析结果显示,与女性、<20岁年龄组、干部职员、健康体检、病原学结果阴性、初治、无合并症、无合并其他结核、HIV检测结果阴性相比,男性(OR=0.736,95%CI:0.709~0.765)、≥60岁年龄组(OR=0.360,95%CI:0.323~0.402)、农民(OR=0.591,95%CI:0.468~0.747)、因症就诊(OR=0.716,95%CI:0.599~0.855)、复治(OR=0.570,95%CI:0.540~0.602)、有合并症(OR=0.789,95%CI:0.752~0.827)、合并其他结核(OR=0.685,95%CI:0.542~0.867)、HIV检测结果阳性(OR=0.387,95%CI:0.342~0.437)是患者成功治疗的危险因素(P均<0.05)。结论贵州省肺结核患者治疗情况总体较好,需进一步关注男性、老年人、毕节市、病原学阳性、HIV阳性、复治、合并症及合并其他结核等患者的治疗问题。Objective To analyze the treatment outcomes and influencing factors among pulmonary tuberculosis patients in Guizhou Province from 2017 to 2022,and to improve a basis for enhancing tuberculosis prevention and control strategies.Methods Individual cases of pulmonary tuberculosis patients in Guizhou Province from 2017 to 2022 were obtained from The Tuberculosis Information Management System.The distribution characteristics of treatment success were described using percentages(%),and the Chi-square test and binary logistic regression model were utilized to analyze the factors influencing treatment outcomes.Results During the period of 2017 to 2022,the annual average registration rate of pulmonary tuberculosis patients in Guizhou Province was 97.27/100000 population,exhibiting a consistent downward trend(trendχ^(2)=2230.684,P<0.001).Meanwhile,the treatment success rate among the patients during the same time period was 92.89%,demonstrating a steady increase(trendχ^(2)=51.800,P<0.001).Analysis results of influencing factors showed that compared with female,age group<20 years old,cadres and staff,physical examination,negative etiological results,initial treatment,no comorbidities,no other tuberculosis,and negative HIV test results,male(OR=0.736,95%CI:0.709-0.765),≥60 years old age group(OR=0.360,95%CI:0.323-0.402),farmers(OR=0.591,95%CI:0.468-0.747),medical treatment due to illness(OR=0.716,95%CI:0.599-0.855),retreatment(OR=0.570,95%CI:0.540-0.602),complications(OR=0.789,95%CI:0.752-0.827),other tuberculosis(OR=0.685,95%CI:0.542-0.867)and positive HIV test results(OR=0.387,95%CI:0.342-0.437)were risk factors for successful treatment(P<0.05).Conclusion Overall,the treatment outcomes of pulmonary tuberculosis patients in Guizhou Province are highly positive.However,it is essential to recognize that there are disparities in the distribution of treatment outcomes across various population groups.Hence,it is recommended to prioritize the treatment concerns of specific demographics,including male patients,the elderly pop

关 键 词：肺结核 治疗成功 影响因素 

分 类 号：R181.3[医药卫生—流行病学] R521[医药卫生—公共卫生与预防医学]