生肌解毒汤联合浸浴治疗烧伤残余创面患者的效果  

Effects of Shengji Jiedu decoction combined with dipping bath on patients with residual burn wounds

作　　者：刘石 李华义 石瑶瑶 LIU Shi;LI Huayi;SHI Yaoyao(Department of Burn and Plastic Surgery of Suqian Hospital of Traditional Chinese Medicine,Suqian 223800 Jiangsu,China)

机构地区：[1]宿迁市中医院烧伤整形科,江苏宿迁223800

出　　处：《中国民康医学》2024年第6期103-106,共4页Medical Journal of Chinese People’s Health

摘　　要：目的:观察生肌解毒汤联合浸浴治疗烧伤残余创面患者的效果。方法:回顾性分析2022年5月至2023年5月该院收治的200例烧伤残余创面患者的临床资料,根据治疗方法不同将其分为对照组与观察组各100例。对照组采用浸浴治疗,观察组在对照组基础上联合生肌解毒汤治疗,比较两组临床疗效,治疗后创面面积,治疗前后疼痛介质(5-羟色胺、神经肽Y、前列腺素E2)水平、疼痛程度[视觉模拟评分法(VAS)]评分、生命质量[简明烧伤专用健康量表(BSHS-A)]评分,以及不良反应发生率。结果:观察组治疗总有效率为95.00%(95/100),高于对照组的82.00%(82/100),差异有统计学意义(P<0.05);治疗3、7、14 d后,观察组创面面积均小于对照组,差异有统计学意义(P<0.05);治疗后,两组5-羟色胺、神经肽Y和前列腺素E2水平均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05);治疗后,两组VAS评分均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05);治疗后,两组躯体功能、心理功能、社会关系、一般健康状况等BSHS-A评分均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05);治疗期间,两组均未出现明显不良反应。结论:生肌解毒汤联合浸浴治疗烧伤残余创面患者可提高治疗总有效率与生命质量评分,缩小创面面积,降低疼痛介质水平和VAS评分,其效果优于单纯浸浴治疗。Objective:To observe effects of Shengji Jiedu decoction combined with dipping bath on patients with residual burn wounds.Methods:The clinical data of 200 patients with residual burn wounds admitted to this hospital from May 2022 to May 2023 were retrospectively analyzed.According to different treatment methods,they were divided into control group and observation group,100 cases in each group.The control group was treated with dipping bath,while the observation group was treated with Shengji Jiedu decoction on the basis of that of the control group.The clinical efficacy,the wound area after the treatment,the pain mediator indexes [5-hydroxytryptamine,neuropeptide Y,prostaglandin E2] levels,the pain degree [visual analogue scale(VAS)] score,the quality of life [concise burn health survey(BSHS-A)] score before and after the treatment,and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of treatment in the observation group was 95.00%(95/100),which was higher than 82.00%(82/100) in the control group,and the difference was statistically significant(P<0.05).After 3,7and 14 days of treatment,the wound areas of the observation group were smaller than those of the control group,and the differences were statistically significant(P<0.05).After the treatment,the levels of 5-hydroxytryptamine,neuropeptide Y and prostaglandin E2 in the two groups were lower than those before the treatment,those in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).After the treatment,the VAS scores of the two groups were lower than those before the treatment,that in the observation group was lower than that in the control group,and the differences were statistically significant(P<0.05).The BSHS-A scores of physical function,psychological function,social relationship and general health status in the two groups were higher than those before the treatment,those in the observation group were higher than those in the cont

关 键 词：生肌解毒汤 浸浴 烧伤残余创面 疼痛介质 生命质量 不良反应 

分 类 号：R644[医药卫生—外科学]