序贯通气治疗在重症急性左心衰竭伴呼吸衰竭患者中的应用效果  

Effect of Sequential Ventilation in Patients with Severe Acute Left Heart Failure with Respiratory Failure

作　　者：马盼盼 李青梅 丁磊 Ma Panpan;Li Qingmei;Ding Lei(Department of Critical Care Medicine,Binzhou Central Hospital,Binzhou 251708,Shandong Province,China)

机构地区：[1]滨州市中心医院重症医学科,山东滨州251708

出　　处：《中外医药研究》2024年第2期24-26,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:探讨序贯通气治疗在重症急性左心衰竭(ALHF)伴呼吸衰竭(RF)患者中的应用效果。方法:选取2021年1月-2022年12月滨州市中心医院收治的重症ALHF伴RF患者140例为研究对象。按照随机数字表法分为对照组和观察组,各70例。对照组采用常规通气治疗,观察组实施序贯通气治疗。比较两组通气时间、住院时间、肺功能指标、呼吸机相关性肺炎发生率。结果:观察组机械通气时间、有创通气时间、住院时间短于对照组,差异有统计学意义(P<0.001);治疗后,两组用力肺活量、呼气峰值流速、第1秒用力呼气容积、最大自主通气量升高,观察组高于对照组,差异有统计学意义(P<0.05);观察组呼吸机相关性肺炎发生率低于对照组,差异有统计学意义(P=0.039)。结论:序贯通气在重症ALHF伴RF患者中的治疗效果较好,能够缩短有创通气时间,促进肺功能改善,减少呼吸机相关性肺炎的发生。Objective:To investigate the effect of sequential ventilation in patients with severe acute left heart failure(ALHF)and respiratory failure(RF).Methods:A total of one hundred and forty patients with severe ALHF and RF treated in Binzhou Central Hospital from January 2021 to December 2022 were selected as the study objects.They were divided into control group and obser-vation group according to random number table method,seventy cases in each group.The control group was treated with routine ventilation,and the observation group was treated with sequential ventilation.Ventilation time,hospital stay,pulmonary function index and incidence of ventilator-associated pneumonia were compared between the two groups.Results:The mechanical ventila-tion time,invasive ventilation time and hospital stay in the observation group were shorter than those in the control group,the dif-ference was statistically significant(P<0.001);after treatment,forced vital capacity,peak expiratory flow rate,forced expiratory volume in the first second and maximum spontaneous ventilation were increased in the two groups,the observation group were higher than those in the control group,and the difference was statistically significant(P<0.05);the incidence of ventilators associ-ated pneumonia in the observation group was lower than that in the control group,and the difference was statistically significant(P=0.039).Conclusion:Sequential ventilation is effective in the treatment of severe ALHF and RF patients,which can shorten the invasive ventilation time,promote the improvement of lung function,and reduce the occurrence of ventilator-associated pneumonia.

关 键 词：重症急性左心衰竭 呼吸衰竭 序贯通气 肺功能 通气时间 

分 类 号：R541.6[医药卫生—心血管疾病]