血常规参数在鉴别诊断儿童传染性单核细胞增多症与急性化脓性扁桃体炎中的价值  

The Value of Routine Blood Parameters in the Differential Diagnosis of Infectious Mononucleosis and Acute Suppurative Tonsillitis in Children

作　　者：陈静[1] 史利欢 谢昕 范朋凯 许哲 CHEN Jing;SHI Lihuan;XIE Xin;FAN Pengkai;XU Zhe(Henan Provincial Key Laboratory of Pediatric Hematology,Affiliated Children’s Hospital of Zhengzhou University,Henan Children’s Hospital,Zhengzhou Children’s Hospital,Zhengzhou Henan 450000,China)

机构地区：[1]郑州大学附属儿童医院,河南省儿童医院,郑州儿童医院河南省小儿血液医学重点实验室,河南郑州450000

出　　处：《临床研究》2024年第4期127-129,共3页Clinical Research

摘　　要：目的探究儿童传染性单核细胞增多症(IM)与急性化脓性扁桃体炎(AST)使用血常规参数鉴别诊断的价值。方法选取郑州大学附属儿童医院38例IM患儿作为实验组研究对象,另外选取38例AST患儿作为对照组研究对象。选取时间为2021年1月至2022年1月。对比两组血常规参数,主要包括炎性血清因子指标[白细胞(WBC)、中性粒细胞/淋巴细胞比值(NLR)、单核细胞/淋巴细胞比值(MLR)、血小板/淋巴细胞比值(PLR)]、血清淋巴细胞参数[淋巴细胞复杂程度(L-X)、淋巴细胞荧光强度(L-Y)、淋巴细胞大小(LZ)]与血清中性粒细胞参数[中性粒细胞复杂程度(N-X)、中性粒细胞荧光强度(N-Y)、中性粒细胞大小(N-Z)]。结果两组WBC检测水平对比差异无统计学意义(P>0.05),实验组NLR、MLR、PLR检测水平低于对照组,差异有统计学意义(P<0.05);两组L-X检测水平对比差异无统计学意义(P>0.05),实验组检测L-Y、LZ水平高于对照组,差异有统计学意义(P<0.05);两组N-Z检测水平对比差异无统计学意义(P>0.05),实验组检测N-X、N-Y水平低于对照组,差异有统计学意义(P<0.05)。结论临床可通过血常规参数NLR、MLR、PLR、L-Y、LZ、N-X、N-Y给予IM、AST辅助鉴别诊断,值得应用。Objective To explore the value of routine blood parameters in the differential diagnosis of infectious mononucleosis(IM)and acute suppurative tonsillitis(AST)in children.Methods 38 children with IM admitted to the Affiliated Children’s Hospital of Zhengzhou University were selected as the experimental group,and another 38 children with AST were selected as the control group.The selection time was from January 2021 to January 2022.The routine blood parameters of the two groups were compared,mainly including inflammatory serum factor indicators[white blood cells(WBC),neutrophil/lymphocyte ratio(NLR),monocyte/lymphocyte ratio(MLR),platelet/lymphocyte ratio(PLR)],serum lymphocyte parameters[lymphocyte complexity(L-X),lymphocyte fluorescence intensity(L-Y),lymphocyte size(LZ)]and serum neutrophil parameters[neutrophil complexity(N-X),neutrophil fluorescence intensity(N-Y),neutrophil size(N-Z)].Results There was no statistical significance in the comparison of WBC detection levels between the two groups(P>0.05),and the NLR,MLR,and PLR detection levels of the experimental group were lower than those of the control group,and the difference was statistically significant(P<0.05);there was no statistical significance in the comparison of L-X detection levels between the two groups(P>0.05),and the L-Y and LZ detection levels of the experimental group were higher than those of the control group,and the difference was statistically significant(P<0.05);there was no statistical significance in the comparison of N-Z detection levels between the two groups(P>0.05),and the N-X and N-Y detection levels of the experimental group were lower than those of the control group,and the difference was statistically significant(P<0.05).Conclusion Clinically,NLR,MLR,PLR,L-Y,LZ,N-X,and N-Y can be used to assist in the differential diagnosis of IM and AST,which is worth applying.

关 键 词：血常规参数 儿童传染性单核细胞增多症 急性化脓性扁桃体炎 鉴别诊断 

分 类 号：R183[医药卫生—流行病学]