置管部位对我国血液病患者PICC相关性血栓影响的meta分析  

Meta-analysis of the impact of catheterization sites on PICC-related thrombosis in Chinese patients with hematological diseases

作　　者：苏醒 马银鑫 邵帅 SU Xing;MA Yinxin;SHAO Shuai(Institute of Hematology&Blood Diseases Hospital,Chinese Academy of Medical Sciences,State Key Laboratory of Experimental Hematology,National Clinical Research Center for Blood Diseases,Haihe Laboratory of Cell Ecosystem,Tianjin Institutes of Health Science,Tianjin 300020,China)

机构地区：[1]中国医学科学院血液病医院(中国医学科学院血液学研究所),实验血液学国家重点实验室,国家血液系统疾病临床医学研究中心,细胞生态海河实验室,天津医学健康研究院,天津300020

出　　处：《中国医药科学》2024年第6期151-154,共4页China Medicine And Pharmacy

基　　金：中国医学科学院医学与健康科技创新工程项目(2021-I2M-C&T-B-085)。

摘　　要：目的系统评价置管部位对我国血液病患者经外周静脉置入中心静脉导管术后相关性血栓的影响,为临床提供借鉴依据。方法检索中英文数据库,时限为2001年1月1日至2023年1月1日,将检索的文献交由2名专业人员筛选与评价,最终纳入的文献采用Review Manager 5.3进行meta分析。结果共纳入9篇文献,总累计病例组188例、对照组1340例,涉及4项影响因素。meta分析结果显示:贵要静脉[OR=0.63,95%CI(0.43,0.94)、P=0.02]、头静脉[OR=2.45,95%CI(1.39,4.34),P=0.002]、置管肢体[OR=0.63,95%CI(0.41,0.96),P=0.03]同其他比较,差异有统计学意义(P<0.05)。结论贵要静脉、左侧置管可降低我国血液病患者导管相关性血栓的发生率,为保护因素;头静脉及右侧置管为危险因素。Objective To systematically evaluate the impact of catheterization sites on related thrombosis in Chinese patients with hematological diseases after peripherally inserted central catheter,and to provide a reference for clinical practice.Methods The Chinese and English databases were retrieved,with the retrieval duration from January 1,2001 to January 1,2023.The retrieved literature was screened and evaluated by two professionals,and a meta-analysis was conducted on the final included literature using Review Manager 5.3.Results A total of 9 articles were included,with a total of 188 patients in the case group and 1340 patients in the control group,involving 4 influencing factors.The meta-analysis results showed that the basilic vein(OR=0.63,95%CI[0.43,0.94],P=0.02),cephalic vein(OR=2.45,95%CI[1.39,4.34],P=0.002),and the limb for catheterization(OR=0.63,95%CI[0.41,0.96],P=0.03)showed statistically significant difference(P<0.05).Conclusion The basilic vein and left catheterization can reduce the incidence of PICC-related VT in patients with hematological diseases in China,being protective factors.The cephalic vein and right catheterization are risk factors.

关 键 词：血液病 经外周静脉置入中心静脉导管 血栓 META分析 

分 类 号：R472[医药卫生—护理学]