内耳钆增强磁共振3D CUBE FLAIR序列PPI及HYDROPS图像在诊断内淋巴积水中的价值  

Value in EH diagnosis of PPI and HYDROPS of 3D CUBE FLAIR based on inner ear magnetic resonace imaing with gadolinium enhancement

作　　者：王子坤 冯晶晶 吴杰[2] 叶玉芳 陈英敏[2] 时媛 吴晶[2] 孙利强 WANG Zikun;FENG Jingjing;WU Jie;YE Yufang;CHEN Yingmin;SHI Yuan;WU Jing;SUN Liqiang(Graduate School,Hebei North University,Zhangjiakou 075000,China;Medical Imaging Center,Hebei Provincial People's Hospital,Shijiazhuang 050051,China)

机构地区：[1]河北北方学院研究生学院,张家口075000 [2]河北省人民医院医学影像科,石家庄050051

出　　处：《磁共振成像》2024年第3期151-157,176,共8页Chinese Journal of Magnetic Resonance Imaging

基　　金：河北省2022年度医学科学研究课题计划项目(编号:20220057)。

摘　　要：目的 探讨经静脉注射钆对比剂行内耳增强磁共振三维快速液体衰减反转恢复序列(three-dimensional fluid attenuated inversion recovery with CUBE,3D CUBE FLAIR)阳性内淋巴影像(positive perilymph image,PPI)及HYDROPS (HYbriD of reversed image of positive endolymph signal and native image of positive perilymph signal)图像在内淋巴积水(endolymphatic hydrops,EH)中的诊断价值。材料与方法 回顾性分析患侧EH、对侧无EH患者资料及MRI图像22例。应用Image J软件在所获图像上勾画感兴趣区,测量同一图像上患侧及健侧的耳蜗底周与同侧小脑白质区信号强度比(signal intensity ratio,SIR)、同一侧前庭外淋巴与内淋巴间隙SIR;对PPI及HYDROPS图像上患侧耳蜗积水数量及前庭积水边界清晰程度评分。评估两种图像对患侧血-迷路屏障(blood-labyrinth barrier,BLB)通透性改变的显示情况、同侧前庭在两种图像上的成像效果、评估两种图像对耳蜗EH敏感性及前庭EH边界的显示情况。结果 PPI图像中患侧及健侧的耳蜗底周与同侧小脑白质区SIR之间的差异具有统计学意义(P<0.001);HYDROPS图像中患侧及健侧耳蜗底周与同侧小脑白质区SIR之间的差异具有统计学意义(P<0.001)。PPI图像及HYDROPS图像上的患侧前庭外淋巴与内淋巴间隙SIR之间的差异具有统计学意义(P<0.001);PPI图像及HYDROPS图像上的健侧前庭外淋巴与内淋巴SIR间隙之间的差异具有统计学意义(P<0.001)。PPI图像及HYDROPS图像诊断耳蜗EH的敏感性之间的差异具有统计学意义(P=0.030)。PPI图像及HYDROPS图像患侧前庭内淋巴间隙边界清晰程度评分之间的差异具有统计学意义(P<0.001)。结论 内耳钆增强磁共振3D CUBE FLAIR序列PPI及HYDROPS图像综合应用,有利于评估患侧BLB通透性、积水部位以及前庭EH边界的显示。Objective:To assess the value in endolymphatic hydrops(EH)diagnosis of positive perilymph image(PPI)and HYDROPS(HYbriD of reversed image of positive endolymph signal and native image of positive perilymph signal)of three-dimensional fluid attenuated inversion recovery with CUBE(3D CUBE FLAIR)based on inner ear magnetic resonance imaging with contrast enhancement following intravenous injection of gadolinium.Materials and Methods:The data and MRI images of 22 patients with EH on the affected side and without EH on the contralateral side were retrospectively analyzed.The Image J software was used to delineate the regions of interest the images obtained to analyze the signal intensity ratios(SIR)of the cochlear basal turn to the same side cerebellar white matter on affected and unaffected sides in the same image and SIRs of perilymph to the same side endolymph of vestibule both in PPI and HYDROPS;Count the numbers of cochlear EH on the affected side and the scores of vestibular EH boundaries definition both in PPI and HYDROPS.Evaluate the visualization of permeability change of the blood-labyrinth barrier(BLB)on the affected side,the vestibular developing effect,the cochlear EH sensibility and the development in vestibular EH boundaries in the two kinds of images.Results:There was statistical difference in SIRs of the cochlear basal turn to the same side cerebellar white matter between affected and unaffected sides in PPI(P<0.001).There was statistical difference in SIRs of the cochlear basal turn to the same side cerebellar white matter between affected and unaffected sides in HYDROPS(P<0.001).There was statistical difference in SIRs of perilymph to the same side endolymph of vestibule between PPI and HYDROPS on the affected side(P<0.001).There was statistical difference in SIRs of perilymph to the same side endolymph of vestibule between PPI and HYDROPS on the unaffected side(P<0.001).There was statistical difference in the sensibility of the cochlear EH diagnosis between PPI and HYDROPS(P=0.030).There was statist

关 键 词：内淋巴积水 耳蜗 前庭 血-迷路屏障 通透性 钆对比剂 信号强度比 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R764[医药卫生—诊断学]