经前期焦虑障碍相关情感回路异常的脑功能成像研究进展  

Advances in brain functional imaging of abnormal emotional circuits associated with premenstrual dysphoric disorder

作　　者：陈思睿 徐小雯 赵阳[1] 肖磊 陈振宇 廖海 CHEN Sirui;XU Xiaowen;ZHAO Yang;XIAO Lei;CHEN Zhenyu;LIAO Hai(Department of Radiology,Guangxi Medical University Cancer Hospital,Nanning 530021,China)

机构地区：[1]广西医科大学附属肿瘤医院放射科,南宁530021

出　　处：《磁共振成像》2024年第3期196-199,217,共5页Chinese Journal of Magnetic Resonance Imaging

基　　金：国家自然科学基金项目(编号:81960570)。

摘　　要：经前期焦虑障碍(premenstrual dysphoric disorder,PMDD)是一种女性独特的情感障碍性疾病,严重影响着育龄期女性的生活健康,目前其发病机制尚不明确。近年研究表明,以“前额叶-前扣带回-杏仁核-海马-小脑”构成的情感回路功能异常可能与PMDD发病密切相关。本文通过综述该情感回路相关脑区及脑区间的脑功能研究,为寻找PMDD的神经病变机制提供参考依据。Premenstrual dysphoric disorder(PMDD)is a unique emotional disease of women,which seriously affects the life and health of women of childbearing age.At present,its pathogenesis is still unclear.Recent studies have shown that the function of affective circuit composed of"prefrontal-anterior cingulate cortex-amygdala-hippocampus-cerebellum"may be closely related to the pathogenesis of PMDD.The paper reviews the brain function of the related brain regions and brain intervals of PMDD,and provide reference for finding the neuropathy mechanism of PMDD.

关 键 词：经前期焦虑障碍 情感障碍 脑功能成像 功能磁共振成像 磁共振成像 前额叶皮层 杏仁核 神经机制 

分 类 号：R445.2[医药卫生—影像医学与核医学] R749.72[医药卫生—诊断学]