儿童心肌炎标志物研究进展  

Progression of markers for nmyocarditis inchildren

作　　者：陈雅娜 陈名武 CHEN Ya-na;CHEN Ming-wu(Department of Cardiology,the First Affiliated Hospital of USTC,Anhui Provincial Hospital,Hefei 230001,China)

机构地区：[1]皖南医学院安徽省立医院,安徽合肥230001

出　　处：《中国实用儿科杂志》2024年第3期198-203,共6页Chinese Journal of Practical Pediatrics

基　　金：2021年高等学校省级质量工程项目(2021jxtd326)。

摘　　要：心肌炎是心肌中有局限或弥漫性的炎症病变,是由组织学、免疫学等方法确认的心肌炎症性疾病。临床上心肌炎诊断的“金标准”是心内膜心肌组织活检,但其缺乏早期诊断的优势。而不能早期诊断是心肌炎致死的重要原因之一。心肌标志物的检测具有早期、快速、便捷等特点,对于心肌炎的早期发现、了解病情、评估疗效均有一定价值。目前常见心肌标志物多用于成人心脏相关疾病的诊断,由于儿童心肌功能尚未成熟、生长发育有特殊性,其心肌损伤的发病机制和病理生理过程与成人大不相同,心肌相关标志物在儿科领域中的应用价值尚不明确。文章就儿童心肌炎标志物的研究进展进行综述。Myocarditis is a local or diffuse myocardial inflammatory disease,which is identified by histological and immunological methods.Clinically,the"gold standard"for the diagnosis of myocarditis has been endocardial biopsy.But it lacks the advantage of early diagnosis,which is an important cause of the death due to myocarditis.The detection of myocardial markers possesses the characteristics of being early,rapid and convenient,thus providing certain value for the early diagnosis,the understanding of the condition and also the evaluation of curative effect in myocarditis patients.At present,common myocardial markers are mostly used for the diagnosis and treatment of adult heart-related diseases.Due to the immaturity of myocardial function and the particularity of growth and development in children,the pathogenesis and pathophysiological process of myocardial injury in children are very different from those in adults.Up to now,there is no clear application value of pediatric myocardial markers.As a result,this article reviews the research progress of markers with myocarditisin in children.

关 键 词：心肌炎 标志物 进展 儿童 

分 类 号：R72[医药卫生—儿科]