A novel small-animal locomotor activity recording device for biological clock research  

作　　者：Yi-Long Wu Ming Zhong Jun Yin Wei-Jie Ou Yu-Bin Zhuang Nan-Wen Zhang Su Lin Yue-Yong Zhu 

机构地区：[1]Endoscopy Center,The First Affiliated Hospital,Fujian Medical University,Fuzhou,China [2]Department of Endocrinology,The First Affiliated Hospital,Fujian Medical University,Fuzhou,China [3]Chuangke Workshop Technology Co.,Ltd,Shenzhen,China [4]Department of Digestive Nutrition,Fujian Children's Hospital,Fuzhou,China [5]Experimental Animal Center,Fujian Medical University,Fuzhou,China [6]Department of Pharmacology,Fujian Medical University,Fuzhou,China [7]Department of Hepatology,Hepatology Research Institute,Clinical Research Center for Liver and Intestinal Diseases of Fujian Province,The First Affiliated Hospital,Fujian Medical University,Fuzhou,China

出　　处：《Animal Models and Experimental Medicine》2024年第1期71-76,共6页动物模型与实验医学（英文）

基　　金：Startup Fund for scientific research,Fujian Medical University,Grant/Award Number:2020QH1039;Joint Funds for the Innovation of Science and Technology,Fujian Province,Grant/Award Number:2020Y9114 and 2020Y9119。

摘　　要：The rodent running-wheel recording apparatus is a reliable approach for studying cir-cadian rhythm.This study demonstrated how to construct a simple and intelligent running-wheel recording system.The running wheel was attached to the cage's base,whereas the Hall sensor was attached to the cage's cover.Then,the RJ25 adaptor relayed the running signal to the main control board.Finally,the main control board was connected to the USB port of the computer with the USB connection.Data were collected using the online-accessible,self-created software Magturning.Through Magturning,generated data were saved and exported in real time.Afterward,the device was validated by collecting data on the locomotor activities of mice under dif-ferent light conditions.In conclusion,this new device can record circadian activity of rodents.Our device is appropriate for interdisciplinary investigations related to biological clock research.

关 键 词：biological clock circadian rhythm intelligent equipment locomotor activity running wheel 

分 类 号：Q95-33[生物学—动物学]