A Comprehensive Overview of the Neural Mechanisms of Light Therapy  

作　　者：Xiaodan Huang Qian Tao Chaoran Ren 

机构地区：[1]Guangdong-Hongkong-Macao Institute of CNS Regeneration,Ministry of Education CNS Regeneration Collaborative Joint Laboratory,Jinan University,Guangzhou 510632,China [2]Psychology Department,School of Medicine,Jinan University,Guangzhou 510632,China

出　　处：《Neuroscience Bulletin》2024年第3期350-362,共13页神经科学通报（英文版）

基　　金：supported by grants from the National Natural Science Foundation of China(32171010 and 32100820);STI2030-Major Projects(2021ZD0203100);the Guangdong Basic and Applied Basic Research Foundation(2023B1515040010).

摘　　要：Light is a powerful environmental factor influencing diverse brain functions.Clinical evidence supports the beneficial effect of light therapy on several diseases,including depression,cognitive dysfunction,chronic pain,and sleep disorders.However,the precise mechanisms underlying the effects of light therapy are still not well understood.In this review,we critically evaluate current clinical evidence showing the beneficial effects of light therapy on diseases.In addition,we introduce the research progress regarding the neural circuit mechanisms underlying the modulatory effects of light on brain functions,including mood,memory,pain perception,sleep,circadian rhythm,brain development,and metabolism.

关 键 词：Light therapy Neural circuit MOOD COGNITION PAIN SLEEP Development METABOLISM 

分 类 号：R338[医药卫生—人体生理学]