戊型肝炎病毒实验感染的动物模型  

Progress in animal models of hepatitis E virus infection

作　　者：耿家宝 熊熙 缪幼菡 赵卫峰[1] Geng Jiabao;Xiong Xi;Miao Youhan;Zhao Weifeng(Department of Infectious Diseases,the First Afiliated Hospital of Soochow University,Suzhou 215000,China;Center of Hepatology and Department of Infectious Diseases,General Hospital of Eastern Theater Command,Nanjing 210002,China;Department of Infectious Diseases,Nantong Third People's Hospital,Nantong 226000,China;First Affiliated Hospital of Soochow University)

机构地区：[1]苏州大学附属第一医院感染病科,苏州215000 [2]东部战区总医院感染病科/肝病中心,南京210002 [3]南通市第三人民医院感染病科,南通226000 [4]苏州大学附属第一医院 [5]东部战区总医院秦淮医疗区感染科

出　　处：《国际流行病学传染病学杂志》2024年第1期63-67,共5页International Journal of Epidemiology and Infectious Disease

摘　　要：戊型肝炎是由HEV引起的常见传染病,它的动物宿主比较广泛,在散发性病例发生过程发挥重要作用。研究HEV动物宿主、实验感染动物模型,对戊型肝炎的防控、HEV致病机制、跨物种传播、疫苗及治疗方案评估等相关研究具有现实意义。本文将对HEV常见动物宿主、实验感染动物模型进行综述。Hepatitis E is a common infectious disease caused by HEV.HEV has a wide range of animal hosts playing an important role in occurrence of sporadic hepatitis E.The study of animal hosts and animal models of HEV infection has important practical significance for the prevention and control of hepatitis E,as well as for understanding the pathogenic mechanisms of HEV,cross species transmission,vaccine and treatment evaluation and other related research.This article reviews the common animal hosts of HEV and animal models of HEV infection.

关 键 词：戊型肝炎病毒 动物宿主 实验感染 动物模型 

分 类 号：R512.6[医药卫生—内科学] R-332[医药卫生—临床医学]