低温射频等离子技术对咽部间隙肿瘤切除患者疼痛及肿瘤复发的影响  

Effect of low temperature radiofrequency plasma technology on pain and tumor recurrence in patients with pharyngeal space tumor resection

作　　者：谭亚洲 杨雪华[1] 郭自奇[1] Tan Ya-zhou;Yang Xue-hua;Guo Zi-qi(Department of Otolaryngology,Anyang Regional Hospital,Anyang 455000,Henan,China)

机构地区：[1]濮阳市安阳地区医院耳鼻咽喉科,河南安阳455000

出　　处：《四川生理科学杂志》2024年第3期633-635,共3页Sichuan Journal of Physiological Sciences

摘　　要：目的:探究低温射频等离子技术对咽部间隙肿瘤切除患者疼痛及肿瘤复发的影响.方法:选取2016年2月至2021年3月期间因咽部间隙肿瘤在我院行手术治疗的患者62例作为研究对象.随机将患者分为对照组和观察组,各31例.对照组采用传统冷刀或热刀切除.观察组采用低温射频等离子技术切除.分析对比两组的围手术期相关指标、术前及术后3 d的疼痛程度和应激反应、术后1 m并发症及1 y内肿瘤复发情况.结果:观察组手术时长、住院时长、手术失血量和黏膜恢复评分均显著低于对照组(P<0.05).两组术前视觉模拟评分法(visual analogue scale,VAS)评分和皮质醇(cortisol,Cor)、前列腺素E2(prostaglandin E2,PGE2)、P物质(substance p,SP)等血清学指标差异无统计学意义(P>0.05);术后第3 d,观察组的VAS评分及各项血清学指标均显著低于对照组(P<0.05).观察组的并发症发生率显著低于对照组(P<0.05).两组的复发率、无进展生存率和总生存率均无显著差异(P>0.05).结论:低温射频等离子技术能改善围术期指标,降低疼痛刺激,具有较高的安全性,且不增加瘤的复发率.Objective:To investigate the effects of low temperature radiofrequency plasma technology on pain and tumor recurrence in patients with pharyngeal space tumor resection.Methods:A total of 62 patients who underwent surgical treatment for pharyngeal space tumors in our hospital from February 2016 to March 2021 were selected as the study objects.The patients were randomly divided into control group and observation group,with 31 cases each.The control group was excised with traditional cold knife or hot knife.The observation group was excised by low temperature RF plasma technique.The perioperative indexes,pain degree and stress reaction before and 3 days after surgery,complications 1 month after surgery and tumor recurrence within 1 year were analyzed and compared between the two groups.Results:Operation duration,hospital stay,operative blood loss and mucosal recovery score in observation group were significantly lower than those in control group(P<0.05).The preoperative visual analogue scale(VAS)scores and cortisol(Cor),prostaglandin E2(PGE2),substance p(SP)were significantly improved in the two (groups.SP)and other serological indexes were not significantly different(P>0.05).On the 3rd day after operation,the VAS scores and serological indexes of the observation group were significantly lower than those of the control group(P<0.05).The complication rate of the observation group was significantly lower than that of the control group(P<0.05).There were no significant differences in recurrence rate,progression-free survival rate and overall survival rate between the two groups(P>0.05).Conclusion:Low temperature radiofrequency plasma technology can improve perioperative indexes,reduce pain stimulation,and has high safety,and does not increase the recurrence rate of tumor.

关 键 词：低温射频等离子技术 经口内镜 咽旁间隙 疼痛 复发 

分 类 号：R473.76[医药卫生—护理学]