百日咳流行病学特征及防控进展  

Epidemiological characteristics and prevention progress of pertussis

作　　者：李宏森 梁疆莉[1,2] 杨净思 LI Hongsen;LIANG Jiangli;YANG Jingsi(Institute of Medical Biology,Peking Union Medical College,Chinese Academy of Medical Sciences,Kunming 650118,Yunnan Province,China;不详)

机构地区：[1]中国医学科学院北京协和医学院医学生物学研究所,云南昆明650118 [2]昆明市新发突发高致病性病原体疫苗研发和产业化企业科技创新中心,云南昆明650118

出　　处：《中国生物制品学杂志》2024年第3期361-369,共9页Chinese Journal of Biologicals

基　　金：云南省重大科技专项计划(202002AA100009)。

摘　　要：百日咳是一种古老的疾病,早期疫苗接种大大降低了百日咳的发病率和病死率。但近年来百日咳再现的情况在全球范围内不断被报道,进一步掌握百日咳流行病学特征,对于研发更有效的百日咳疫苗以及更好地防控和早日消除百日咳至关重要。本文主要就国内外百日咳基本流行特征、血清和分子流行病学特征以及防控进展作一综述。Pertussis is an ancient disease,and early vaccination has greatly reduced the incidence and mortality of pertussis.However,the pertussis resurgence has been reported worldwide in recent years.Further understanding of the epidemiological characteristics of pertussis is essential for the development of more effective pertussis vaccines and for better prevention and control and early elimination of pertussis.This paper mainly reviews the basic epidemiological characteristics,seroepidemiological characteristics,molecular epidemiological characteristics and prevention and control progress of pertussis at home and abroad.

关 键 词：百日咳 百日咳再现 流行病学特征 

分 类 号：R516.6[医药卫生—内科学]