消水圣愈汤治疗老年肺源性心脏病临床观察  

Effect of Xiaoshui Shengyu Decoction in the Treatment of Aged Pulmonary Heart Disease

作　　者：王欢[1] WANG Huan(Department of Geriatrics,The First Affiliated Hospital of China Medical University,Liaoning Province,Shenyang 110001,China)

机构地区：[1]中国医科大学附属第一医院老年医学科,辽宁沈阳110001

出　　处：《中国中医药现代远程教育》2024年第10期62-64,共3页Chinese Medicine Modern Distance Education of China

摘　　要：目的探讨消水圣愈汤对老年慢性肺源性心脏病(CPHD)患者血栓前状态指标及血清白细胞介素-8(IL-8)和肽素(Copeptin)水平的影响。方法将117例老年CPHD患者随机分为对照组(58例)和试验组(59例)。对照组予常规对症治疗,试验组在对照组的基础上予消水圣愈汤治疗,两组均治疗4周。比较两组临床疗效、血栓前状态指标及血清IL-8、Copeptin水平。结果治疗后,试验组总有效率为94.92%(56/59),高于对照组的79.31%(46/58)(P<0.05)。与对照组比较,试验组治疗后血浆黏度、血浆纤维蛋白原(FIB)水平、血清D-二聚体(D-D)、血管性假血友病因子(vWF)、内皮素(ET-1)水平较低,血清IL-8、Copeptin水平较低(P<0.05)。结论消水圣愈汤能明显改善老年CPHD患者血栓前状态,减轻炎症反应,促进心功能恢复,临床疗效显著。Objective To investigate the effects of Xiaoshui Shengyu decoction on the prethrombotic state indexes and serum interleukin-8(IL-8)and Copeptin levels in aged chronic pulmonary heart disease(CPHD).Methods 117 aged patients with CPHD were randomly divided into control group with 58 cases and treatment group with 59 cases.The control group was treated with conventional symptomatic treatment,while the treatment group was treated with Xiaoshui Shengyu decoction on the basis of the control group.The two groups were both treated for 4 weeks.The clinical efficacy,prethrombotic state indexes and serum IL-8 and Copeptin levels were compared between the two groups.Results After treatment,the total effective rate of the treatment group(94.92%,56/59)was higher than that of the control group(79.31%,46/58)(P<0.05).Compared with the control group,the plasma viscosity,plasma fibrinogen(FIB)level,serum D-dimer(D-D),von Willebrand factor(vWF)and endothelin(ET-1)levels were lower,and the serum IL-8 and Copeptin levels were lower in the treatment group after treatment(P<0.05).Conclusion Xiaoshui Shengyu decoction can significantly improve the prethrombotic state of aged CPHD patients,reduce inflammatory reaction,and promote the recovery of cardiac function,with significant clinical effect.

关 键 词：肺胀 慢性肺源性心脏病 老年病 阳虚水泛证 消水圣愈汤 中医药疗法 

分 类 号：R259[医药卫生—中西医结合]