基于少阳枢机理论分期辨治帕金森病“开-关”现象  

Staged treatment of‘open-close'phenomenon in Parkinson's disease based on Shaoyang pivottheory

作　　者：刘鑫 范靖琪 严明月 黎颖佳 陈缘缘 庄礼兴[3] LIU Xin;FAN Jingqi;YAN Mingyue;LI Yingjia;CHEN Yuanyuan;ZHUANG Lixing(The First Clinical College of Guangzhou University of Chinese Medicine,Guangzhou 510410,China;‘The Clinical Medical College of Acupuncture Moxibustion and Rehabilitation of Guangzhou University of Chinese Medicine,Guangzhou 510006,China;The First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510410,China)

机构地区：[1]广州中医药大学第一临床医学院,广州510410 [2]广州中医药大学针灸康复临床医学院,广州510006 [3]广州中医药大学第一附属医院,广州510410

出　　处：《中华中医药杂志》2024年第3期1324-1327,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金面上项目(No.82174486),庄礼兴广东省名中医传承工作室建设项目(No.粤中医办函[2018]5号)。

摘　　要：帕金森病“开-关”现象是帕金森病的重要运动并发症之一,“开”期与“关”期的症状波动严重影响患者日常生活。少阳枢机不利是帕金森病“开-关”现象的根本病机,治疗上分为“开”期开折与“关”期合折两个时期,以和解枢机为主要治疗原则,使用小柴胡汤作为主方进行加减化裁、分期辨治,或运枢转合,或运枢转开,令枢机调畅,“开-关”自解。The‘open-close'phenomenon is one of the serious motor complications of Parkinson's disease,and the motor fluctuation during the ‘on'and‘close'periods seriously affects patients daily life.The dysfunction of the Shaoyang pivot is the source of‘open-close'phenomenon.The treatment is divided into‘on'period and‘close'period,the main principle of treatment is harmonizing the pivot mechanism,and using Xiao Chaihu Decoction as main formula for adjusting.It can be treated in stages,either rotate the pivot to close or rotate the pivot to open,the pivot revolves normally,then‘open-close'phenomenonisreleased.

关 键 词：帕金森病 “开-关”现象 运动障碍 症状波动 少阳枢机 

分 类 号：R277.7[医药卫生—中医学]