筛区注射甲泼尼龙琥珀酸钠治疗急性期贝尔面瘫疗效观察  

Observation on the Therapeutic Effect of Methylprednisolone Sodium Succinate Injection in the Screening Area for Acute Bell Palsy

作　　者：郑云雪 李国徽[2] 陈佳[2] 陈腾玉 ZHENG Yunxue;LI Guohui;CHEN Jia;CHEN Tengyu(School of Traditional Chinese Medicine,Ningxia Medical University,Yinchuan 750004;Yinchuan Hospital of Traditional Chinese Medicine affiliated to Ningxia Medical University,Yinchuan 750001;Shaanxi University of Traditional Chinese Medicine,Xianyang 712046)

机构地区：[1]宁夏医科大学中医学院,银川750004 [2]宁夏医科大学附属银川市中医医院,银川750001 [3]陕西中医药大学,咸阳712046

出　　处：《宁夏医科大学学报》2024年第2期170-175,共6页Journal of Ningxia Medical University

基　　金：宁夏回族自治区重点研发计划项目(2020BEG03036);陕西中医药大学校级课题(2021FS14)。

摘　　要：目的观察筛区注射甲泼尼龙琥珀酸钠治疗急性期贝尔面瘫的临床疗效。方法将急性期贝尔面瘫120例随机分为两组,筛区注射组60例(筛区注射甲泼尼龙琥珀酸钠+普通针刺),口服给药组60例(口服泼尼松片+普通针刺),对患者治疗第0、5、10、15、20、30天进行临床疗效评价,采用面神经功能评价分级系统(H-B)及面部残疾指数量表(FDI),比较两组治疗前后的临床疗效,并对耳后疼痛持续时长、不良反应发生情况进行统计。结果筛区注射组有效率为88.33%,口服激素组为90.00%,两组比较差异无统计学意义(P>0.05);治疗前后各时间段两组患者H-B评级、FDI评分比较差异均无统计学意义(P均>0.05);治疗前两组患者耳后疼痛开始时间及入院时间差异均无统计学意义(P均>0.05),治疗后,筛区注射组较口服激素组患者耳后疼痛持续时长缩短(P<0.001)。结论筛区注射给药与全身给药均可获得满意疗效;筛区注射给药可缩短耳后疼痛时长;两组均无严重不良反应发生,筛区注射给药方式值得临床推广。Objective To observe.the clinical efficacy of methylprednisolone sodium succinate injection in the screening area in the treatment of Bell palsy in the acute stage.Methods The 120 cases of Bell palsy in the acute stage were randomly divided into 2 groups,60 cases in the sieve injection group(sieve injection of methylprednisolone sodium succinate+ordinary acupuncture),and 60 cases in the oral hormone group(oral prednisone tablets+ordinary acupuncture),and the clinical efficacy of the patients was evaluated on the day0,5,10,15,20 and 30 day of treatment.The facial nerve function evaluation grading system(H-B)and facial disability index scale(FDI)were used to compare the clinical efficacy of the two groups before and after treatment,and the duration of pain behind the ear and the occurrence of adverse reactions were statistical.Results The effective rate was 88.33%in the sieve injection group and 90.00%in the oral hormone group,and there was no significant difference between the two groups(P>0.05);there was no significant difference in H-B rating and FDI score between the two groups in the time period before and after treatment(P all>0.05);there was no significant difference in the onset time and admission time of behind the ear pain in the two groups before treatment(P all>0.05),and the duration of post-treatment sieve injection group was shorter than that in the oral hormone group(P<0.001).Conclusion Both sieve injection administration and systemic administration can obtain satisfactory efficacy.Sieve injection can significantly shorten the duration of pain behind the ear.There was no incidence of serious adverse reactions in either group,and the sieve injection administration method is worthy of clinical promotion.

关 键 词：筛区 筛区注射 甲泼尼龙琥珀酸钠 贝尔面瘫 疗效观察 

分 类 号：R246.6[医药卫生—针灸推拿学]