Moyamoya syndrome may result from psoriasis: Four case reports  

作　　者：Zhi-Ying Chen Xiao-Qin Yu Yuan-Yuan Xiang Ling-Hua Liu Xiao-Ping Yin 

机构地区：[1]Department of Neurology,The Affiliated Hospital of Jiujiang University,Jiujiang 332000,Jiangxi Province,China [2]Department of Dermatology,The Affiliated Hospital of Jiujiang University,Jiujiang 332000,Jiangxi Province,China

出　　处：《World Journal of Clinical Cases》2024年第10期1830-1836,共7页世界临床病例杂志

摘　　要：BACKGROUND Moyamoya syndrome(MMS)is a group of diseases that involves more than one underlying disease and is accompanied by moyamoya vascular phenomena.Psoriasis is a chronic immune skin disease closely linked to high blood pressure and heart disease.However,psoriasis-related MMS has not been reported.CASE SUMMARY We collected data on patients with stroke due to MMS between January 2017 and December 2019 and identified four cases of psoriasis.Case histories,imaging,and hematological data were collected.The average age of the initial stroke onset was 58.25±11.52 years;three cases of hemorrhagic and one case of ischemic stroke were included.The average duration from psoriasis confirmation to the initial MMS-mediated stroke onset was 17±3.56 years.All MMS-related stenoses involved the bilateral cerebral arteries:Suzuki grade III in one case,grade IV in two cases,and grade V in one case.Abnormally elevated plasma interleukin-6 levels were observed in four patients.Two patients had abnormally elevated immunoglobulin E levels,and two had thrombocytosis.All four patients received medication instead of surgery.With an average follow-up time of 2 years,two causing transient ischemic attacks occurred in two patients,and no hemorrhagic events occurred.CONCLUSION Psoriasis may be a potential risk factor for MMS.Patients with psoriasis should be screened for MMS when they present with neurological symptoms.

关 键 词：Moyamoya syndrome PSORIASIS Stroke INTERLEUKIN-6 IMMUNE HYPERTENSION Case report 

分 类 号：R597[医药卫生—内科学]