肿瘤射频消融技术及临床应用研究进展  

Advances in Radiofrequency Ablation Techniques and Clinical Applications of Tumors

作　　者：黄川骅 刘宝林[1] HUANG Chuanhua;LIU Baolin(School of Health Science and Engineering,University of Shanghai for Science and Technology,Shanghai Tumor Energy Therapy Technology and Device Collaborative Innovation Center,Shanghai 200093,China)

机构地区：[1]上海理工大学健康科学与工程学院,上海市肿瘤能量治疗技术与器械协同创新中心,上海200093

出　　处：《生物医学工程学进展》2024年第1期54-64,共11页Progress in Biomedical Engineering

摘　　要：目的该研究旨在探讨射频消融在大尺寸肿瘤中存在的技术难题及解决方法,以提高射频消融技术在临床治疗中的应用效果。方法该研究基于射频消融的原理,分析“降滚”现象对大尺寸肿瘤完全消融的限制,并探讨大血管散热引起的消融不完全问题,从而引出在射频消融中应用数学建模仿真来判断消融损伤程度的方法。结果和结论该研究基于相关研究现状,强调数学建模仿真在射频消融中的作用,即术前模拟以预测消融效果,指导临床优化治疗方案以提高治疗效果。创新之处该研究总结了优化消融器械设计、模拟仿真等措施以改进治疗效果,并展望了射频消融技术的发展方向,如引入肿瘤联合治疗和智能化技术,以提高射频消融的精准性和完全性。Objective This study aims to explore the technical problems and solutions of radiofrequency ablation in large tumors,so as to improve the efficacy of radiofrequency ablation in clinical treatment.Methods Based on the principle of radiofrequency ablation,the limitation of“rolling down”phenomenon on the complete ablation of large tumors was analyzed,and the incomplete ablation caused by heat dissipation of large blood vessels was discussed,so as to introduce the mathematical modeling and simulation method used in radiofrequency ablation to judge the degree of ablation damage.Results and conclusions Based on relevant research status,the role of mathematical modeling and simulation in radiofrequency ablation was emphasized,that is,preoperative simulation to predict the ablation effect and guide clinical optimization of treatment plan to improve treatment effect.Innovation Methods to optimize ablation device design,simulation and other measures to improve the therapeutic effect are summarized,and the development direction of radiofrequency ablation is prospected,such as the introduction of tumor combination therapy and intelligent technology to improve the accuracy and completeness of radiofrequency ablation.

关 键 词：射频消融 降滚 大尺寸肿瘤 血管散热 建模仿真 

分 类 号：R318[医药卫生—生物医学工程]