冠心病患者小而密低密度脂蛋白胆固醇与低密度脂蛋白胆固醇水平特点分析  

Characterisation of small and dense low-density lipoprotein cholesterol and low-density lipoprotein cholesterol levels in patients with coronary heart disease

作　　者：秦庆双 QIN Qingshuang(Department of Laboratory,Linyi Hospital of Traditional Chinese Medicine,Linyi,Shandong 276000,China)

机构地区：[1]临沂市中医医院检验科,山东临沂276000

出　　处：《医药前沿》2024年第10期28-30,共3页Journal of Frontiers of Medicine

摘　　要：目的:分析冠心病患者小而密低密度脂蛋白胆固醇(sdLDL-C)与低密度脂蛋白胆固醇(LDL-C)水平的特点。方法:选取2022年1—12月临沂市中医医院收治的86例冠心病患者(作为试验组),以及86名同期进行健康体检者(作为对照组)为研究对象,收集两组研究对象sdLDL-C、LDL-C水平及sdLDL-C/LDL-C,以及试验组研究对象冠状动脉病变严重程度、颈动脉内膜厚度(IMT)等资料,分析冠心病患者sdLDL-C、LDL-C水平及sdLDL-C/LDL-C及其与病变严重程度的相关性。结果:试验组研究对象sdLDL-C、LDL-C水平及sdLDL-C/LDL-C均高于对照组,差异有统计学意义(P<0.05)。gensini评分越高及IMT越大的冠心病患者sdLDL-C、LDL-C水平及sdLDL-C/LDL-C越高,差异有统计学意义(P<0.05)。结论:冠心病患者sdLDL-C、LDL-C水平及sdLDL-C/LDL-C高于正常体检者,且病变程度越高的冠心病患者sdLDL-C、LDL-C水平及sdLDL-C/LDL-C越高。Objective To analyse the characteristics of small and dense low-density lipoprotein cholesterol(sdLDL-C)and low-density lipoprotein cholesterol(LDL-C)levels in patients with coronary artery disease.Methods 86 patients with coronary artery disease admitted to Linyi Hospital of Traditional Chinese Medicine from January to December 2022(as the experimental group)and 86 people who underwent health check-ups during the same period(as the control group)were selected as the subjects,and information on sdLDL-C,LDL-C levels and sdLDL-C/LDL-C were collected in both groups,as well as on the experimental group coronary artery lesion severity and carotid intima-media thickness(IMT)were collected to analyse sdLDL-C,LDL-C,sdLDL-C/LDL-C and their correlation with lesion severity in patients with coronary artery disease.Results The sdLDL-C,LDL-C levels and sdLDL-C/LDL-C of the experimental group were higher than those in the control group,and the difference was statistically significant(P<0.05).sdLDL-C,LDL-C levels and sdLDL-C/LDL-C were higher in patients with coronary artery disease who had higher Gensini scores and larger IMTs,and the difference was statistically significant(P<0.05).Conclusions The sdLDL-C,LDL-C levels and sdLDL-C/LDL-C were higher in patients with coronary artery disease than in those with normal physical examination,and the higher the degree of lesion,the higher the sdLDL-C,LDL-C levels and sdLDL-C/LDL-C in patients with coronary artery disease.

关 键 词：冠心病 小而密低密度脂蛋白胆固醇 低密度脂蛋白胆固醇 诊断价值 

分 类 号：R541.4[医药卫生—心血管疾病]