特应性皮炎伴双眼视网膜脱离及视网膜血管炎1例  

Atopic Dermatitis Associated Retinal Detachment and Retinal Vasculitis:A Case

作　　者：程世瑜 王造文[1] 戴荣平[1,2] Shi-Yu Cheng;Zao-Wen Wang;Rong-Ping Dai(Department of Ophthalmology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China;Key Laboratory of Ocular Fundus Diseases,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China)

机构地区：[1]中国医学科学院北京协和医学院北京协和医院眼科,北京100730 [2]中国医学科学院北京协和医学院眼底病重点实验室,北京100730

出　　处：《Chinese Medical Sciences Journal》2024年第1期74-78,I0008,共6页中国医学科学杂志（英文版）

摘　　要：特应性皮炎可伴有多种眼部并发症,如结膜炎、角膜炎、白内障和视网膜脱离等。我们报道了1例因双眼视网膜脱离及白内障就诊于眼科的21岁中国男性患者。该患者8年前诊断为特应性皮炎,并接受氯雷他定和吡美莫司治疗。我们为该患者进行了双眼白内障摘除术、右眼巩膜外加压术,以及左眼玻璃体切除及硅油填充术。术后随访期间,患者的特应性皮炎加重,眼底荧光素血管造影结果显示双眼视网膜血管广泛渗漏和左眼黄斑水肿。随后患者至皮肤科接受4个月规律的度普利尤单抗治疗,左眼黄斑水肿好转,术后3年眼部情况一直保持稳定。Atopic dermatitis is usually associated with various ocular complications.We report a 21-year-old Chinese male who presented to our ophthalmology clinic with bilateral retinal detachment and cataracts.The patient had a clear medical history of atopic dermatitis,which had been diagnosed eight years earlier and had been treated with loratadine and pimecrolimus.Cataract surgery was performed for both eyes,combined with scleral buckling for the right eye and pars plana vitrectomy for the left eye.During postoperative follow-up,fundus fluorescein angiography showed retinal vasculitis in both eyes and macular edema in the left eye,which coincided with an exacerbation of atopic dermatitis.Macular edema improved after four months of regular dupilumab treatment in the dermatology department.The ocular condition remained stable three years postoperatively.

关 键 词：特应性皮炎 视网膜脱离 视网膜血管炎 

分 类 号：R758.2[医药卫生—皮肤病学与性病学] R774.1[医药卫生—临床医学]