基于《中华医典》挖掘清代古籍治疗腹痛的用药规律  

Medication rules in treating abdominal pain in ancient books of Qing Dynasty based on Chinese Medicine Canon

作　　者：李清梅[1] 李绅绅 江水玉 覃靖燊 张涛[2] LI Qingmei;LI Shenshen;JIANG Shuiyu;TAN Jingshen;ZHANG Tao

机构地区：[1]广西中医药大学,广西南宁530000 [2]广西中医药大学附属瑞康医院,广西南宁530000

出　　处：《中医临床研究》2024年第3期115-120,共6页Clinical Journal Of Chinese Medicine

基　　金：广西自然科学基金(2019JJA140188)。

摘　　要：目的:对清代古籍中腹痛医案的用药进行数据挖掘研究,以分析清代医家治疗腹痛的组方用药规律,了解该时期的学术思想并为临床实践提供经验。方法:以第5版《中华医典》为资料来源,检索清朝时期治疗腹痛的有效处方并建立数据库,运用古今医案云平台(V2.3.5)所包含的关联规则、聚类分析及复杂网络分析系统等数据挖掘方法,归纳出治疗腹痛处方的高频药物、药物组合规律及核心处方。结果:共筛选出196首有效处方,使用中药202味,其中频次大于10次的中药共有34味,以甘草、白芍、当归、白术、茯苓、陈皮使用频次较高,共总结了4组高频药物,常用关联药物组合22对,核心处方1个。结论:清代治疗腹痛多以补虚药、温里药、理气药等为主,药物以甘温为主,归经多入脾、胃经,以厚朴-陈皮,白术-茯苓,陈皮-白术,茯苓-陈皮,苍术-甘草,当归-白芍等药对相互配伍,运用温中补虚、理气健脾、清热解毒、燥湿祛痰、养血和血、柔肝缓急等方式,以聚类分析的“清”“和”“温”“补”为治疗大法,并从“脾胃虚寒证”“痰湿阻滞证”“气血失和证”三大证型出发,得到一个新处方,探讨了清代治疗腹痛的处方及用药特点,了解了该时期的思想特色,也为现代中医药治疗腹痛开辟新的思考方式。Objective:To conduct data mining research on the medication of the cases of abdominal pain recorded in ancient books of Qing Dynasty(清代),and analyze the rules of prescription and medication in the treatment of abdominal pain by the doctors of Qing Dynasty,so as to understand the academic thoughts of this period and provide experience for clinical practice.Methods:Taking the fifth edition of Chinese Medicine Canon as the data source,the effective prescriptions for the treatment of abdominal pain in the Qing Dynasty were retrieved and a database was established.The high-frequency drugs,combination rules and core prescriptions for the treatment of abdominal pain were summarized by the association rules,cluster analysis and complex network analysis system contained in the ancient and modern medical records cloud platform(V2.3.5).Results:A total of 196 effective prescriptions were screened,and 202 TCM flavors were used,among which 34 TCM flavors were used more than 10 times including Gancao(Glycyrrhiza uralensis Fisch),Baishao(Radix paeoniae alba),Danggui(Radix angelicae sinensis),Baizhu(Rhizoma macrocephalae),Fuling(Poria Cocos) and Chenpi(Pericarpium citri reticulatae).Four groups of highfrequency drugs were summarized,There were 22 pairs of commonly used associated drug combinations and 1 core prescription.Conclusion:In Qing Dynasty,abdominal pain was mainly treated with deficiency tonifying medicine,internal warming medicine,Qi(气) regulating medicine,etc.The drugs were mainly sweet and warm,the channel of tropism included the spleen and stomach meridians,and the drug pairs such as Houpo(Cortex Magnoliae Officinalis)-Chenpi,Baizhu-Fuling,Chenpi-Baizhu,Fuling-Chenpi,Cangzhu(Rhizoma Atractylodis)-Gancao,and DangguiBaishao were compatible with each other.Using the methods of warming and tonifying deficiency,regulating Qi and invigorating the spleen,clearing heat and detoxifying,removing dampness and expelling phlegm,nourishing blood and harmonizing blood,soothing liver and relieving the acute symptoms,etc.,metho

关 键 词：腹痛 《中华医典》 数据挖掘 用药规律 古今医案云平台 

分 类 号：R256.33[医药卫生—中医内科学]