CT影像学特征在儿童腹膜后神经母细胞瘤和神经节神经母细胞瘤鉴别中的作用  

Differences in CT imaging features between retroperitoneal neuroblastoma and ganglion neuroblastoma in children

作　　者：韦平 高彦 高利利 苏睿 WEI Ping;GAO Yan;GAO Lili;SU Rui(Department of Medical Imaging,Jinan Eighth People's Hospital,Jinan,Shandong 271100,China;Department of Special Examination,Jinan Eighth People's Hospital,Jinan,Shandong 271100,China;Department of Laboratory,Jinan Eighth People's Hospital,Jinan,Shandong 271100,China)

机构地区：[1]济南市第八人民医院医学影像科,山东济南271100 [2]济南市第八人民医院特检科,山东济南271100 [3]济南市第八人民医院检验科,山东济南271100

出　　处：《影像研究与医学应用》2024年第5期13-15,共3页Journal of Imaging Research and Medical Applications

基　　金：济南市卫生健康委员会第二批科技计划项目(2020-4-144)。

摘　　要：目的:探讨CT影像学特征在儿童腹膜后神经母细胞瘤和神经节细胞瘤鉴别中的作用。方法:回顾性收集2012年1月—2020年12月于济南市第八人民医院经手术或穿刺病理证实为神经母细胞瘤的24例患儿为观察组,并选取良性神经节神经母细胞瘤(GBN)27例为对照组,对比分析两组患者的CT影像学特征。结果:两组间比较,对照组钙化位置多为偏心型,观察组钙化位置分布相似(P <0.05);对照组钙化形状更多见微钙化和粗大钙化,观察组钙化形状更多见混合钙化(P<0.05);对照组微钙化密度多为很高,观察组均稍高(P <0.05);对照组钙化清晰,观察组钙化多为模糊及部分清晰(P <0.001)。两组患者肿块最大径、肿块截面积差异有统计学意义(P <0.05)。钙化位置、形态、微钙化密度分级、清晰度、钙化灶数目、平均钙化密度、肿块最大径、肿块截面积均是NB的独立影响因素(P <0.05)。结论:CT影像学特征在儿童腹膜后神经母细胞瘤和神经节神经母细胞瘤中具有差异表现,CT影像学特征在儿童腹膜后神经母细胞瘤和神经节神经母细胞瘤鉴别中具有重要作用。Objective To explore the differential manifestations of CT calcification features in children with retroperitoneal neuroblastoma(NB) and ganglion neuroblastoma(GNB).Methods A retrospective collection was performed for 24 children with neuroblastoma confirmed by surgery or puncture pathology in the Jinan Eighth People's Hospital from January 2012 to December 2020 as the observation group,and 27 cases of benign GNB were selected as the control group.Comparative analysis of CT imaging characteristics between two groups of patients.Results The comparison between the two groups showed that the calcification sites in the control group were mostly eccentric,while the distribution of calcification sites in the observation group was similar(P <0.05);The control group had more microcalcifications and coarse calcifications in shape,while the observation group had more mixed calcifications in shape(P < 0.05);The microcalcification density in the control group was mostly very high,while in the observation group it was slightly higher(P < 0.05);The control group had clear calcification,while the observation group had mostly blurred and partially clear calcification(P < 0.001).There were statistically significant difference in the maximum diameter and cross-sectional area of the tumor between the two groups of patients(P < 0.05).The location,morphology,microcalcification density grading,clarity,number of calcified lesions,average calcification density,maximum diameter of the mass,and cross-sectional area of the mass were all independent influencing factors of NB(P < 0.05).Conclusion CT imaging features are different between retroperitoneal neuroblastoma and gangliocytoma in children.CT imaging features play an important role in the differential diagnosis of retroperitoneal neuroblastoma and ganglion neuroblastoma in children.

关 键 词：CT钙化特征 儿童 腹膜后神经母细胞瘤 神经节神经母细胞瘤 

分 类 号：R445.3[医药卫生—影像医学与核医学]