樟木化学成分研究  

Chemical Constituents of Cinnamomum camphora

作　　者：陈芳有 周健[2] 吴华强[1] 姜涛 罗永明[1] CHEN Fang-you;ZHOU Jian;WU Hua-qiang;JIANG Tao;LUO Yong-ming(College of Pharmacy,Jiangxi University of Chinese Medicine,Nanchang 330004,China;Department of Pharmacy,the First Affiliated Hospital of Nanchang University,Nanchang 330006,China)

机构地区：[1]江西中医药大学药学院,江西南昌330004 [2]南昌大学第一附属医院药学部,江西南昌330006

出　　处：《中药材》2023年第8期1942-1945,共4页Journal of Chinese Medicinal Materials

基　　金：江西省赣鄱英才555工程项目(5251500119);江西中医药大学校级科技创新团队发展计划(CXTD22015)。

摘　　要：目的:研究樟木的化学成分。方法:采用多种色谱技术和波谱学方法对樟木乙醇提取物中的化学成分进行分离、纯化和结构鉴定。结果:从樟木中分离得到12个化合物,分别鉴定为:3′,4′-dihydroxy-1,2,6-trimethoxy-[1,1′-biphenyl]-4(1H)-one(1)、spiropreussomerin A(2)、(-)-lyoniresinol(3)、(+)-lyoniresinol(4)、异落叶松树脂素(5)、9-羟基芝麻素(6)、9-hydroxyl piperonol(7)、l-细辛脂素(8)、松脂醇(9)、6,7-二甲氧基香豆素(10)、(R)-(+)-5-(2,3-dihydroxypropyl)-1,3-benzodioxole(11)、3,4,5-三甲氧基苄醇(12)。结论:其中,化合物1、2、4、7、11和12为首次从樟属植物中分离得到,化合物3、5为首次从该植物中分离得到。Objective:To study the chemical constituents of Cinnamomum camphora.Methods:Several chromatographic methods and spectroscopy techniques were used to isolate,purify and identify the chemical constituents from the ethanol extract of Cinnamomum camphora.Results:Twelve compounds were isolated from Cinnamomum camphora and identified as 3′,4′-dihydroxy-1,2,6-trimethoxy-[1,1′-biphenyl]-4(1H)-one(1),spiropreussomerin A(2),(-)-lyoniresinol(3),(+)-lyoniresinol(4),isolariciresinol(5),9-hydrox-ysesamin(6),9-hydroxyl piperonol(7),l-asarinin(8),pinoresinol(9),6,7-dimethoxycoumarin(10),(R)-(+)-5-(2,3-dihydroxyprop-yl)-1,3-benzodioxole(11),3,4,5-trimethoxybenzyl alcohol(12),respectively.Conclusion:Among them,compounds 1,2,4,7,11,12 are isolated from Cinnamomum genus for the first time,compounds 3,5 are isolated from Cinnamomum camphora for the first time.

关 键 词：樟木 木脂素 苯醌衍生物 螺二萘类化合物 

分 类 号：R284.1[医药卫生—中药学] R284.2[医药卫生—中医学]