半枫荷叶正丁醇部位的化学成分研究  

Chemical Constituents of n-Butanol Extract from the Leaves of Semiliquidambar cathayensis

作　　者：裘硕 陈月圆[1] 孙佳祺 李典鹏[1] 卢凤来[1] 颜小捷[1] QIU Shuo;CHEN Yue-yuan;SUN Jia-qi;LI Dian-peng;LU Feng-lai;YAN Xiao-jie(Guangxi Institute of Botany,Chinese Academy of Science,Guangxi Zhuang Autonomous Region/Guangxi Key Laboratory of Plant Functional Phytochemicals and Sustainable Utilization,Guilin 541006,China;Guilin Medical University,Guilin 541006,China)

机构地区：[1]广西壮族自治区中国科学院广西植物研究所/广西植物功能物质与资源持续利用重点实验室,广西桂林541006 [2]桂林医学院,广西桂林541006

出　　处：《中药材》2023年第8期1946-1950,共5页Journal of Chinese Medicinal Materials

基　　金：广西自然科学基金项目(2020GXNSFBA297055);广东省重点领域研发计划项目(2020B1111110003);广西科学院基本科研业务费(2019YJJ1003);桂林市创新平台和人才计划(20210102-3)。

摘　　要：目的:研究半枫荷叶正丁醇部位的化学成分。方法:采用柱色谱和半制备高效液相色谱分离技术对半枫荷叶丙酮提取物的正丁醇部位进行分离纯化,并通过化合物的理化性质和一维核磁共振波谱数据进行化合物结构鉴定。结果:从半枫荷叶丙酮提取物的正丁醇部位中分离得到13个化合物,分别鉴定为:新绿原酸(1)、4-羟基-2-甲氧基苯酚-1-O-β-D-(6′-O-没食子酰基)-葡萄糖苷(2)、4-羟基-3-甲氧基苯酚-1-O-β-D-(6′-O-没食子酰基)-葡萄糖苷(3)、芦丁(4)、金丝桃苷(5)、异槲皮苷(6)、山柰酚-3-O-β-D-芸香糖苷(7)、紫云英苷(8)、杨梅素-3-O-(6″-没食子酰基)-β-D-吡喃葡萄糖苷(9)、山柰酚-3-O-α-L-鼠李糖苷(10)、二氢杨梅素(11)、紫云英苷-6″-O-没食子酸酯(12)、杨梅素-3-O-(6″-没食子酰基)-β-D-半乳糖苷(13)。结论:以上13个化合物均为首次从该植物中分离得到。Objective:To study the chemical constituents of n-butanol extract from the leaves of Semiliquidambar cathayensis.Methods:The compounds from the n-butyl alcohol faction of acetone extract of the leaves of Semiliquidambar cathayensis were isolated and purified by column chromatography and semi-preparative HPLC,the structures were identified by means of physicochemical proper-ties and 1D-NMR spectra data.Results:Thirteen compounds were isolated from the n-butanol faction of acetone extract of the leaves of Semiliquidambar cathayensis and identified as neochlorogenic acid(1),4-hydroxy-2-methoxyphenol-1-O-β-D-(6′-O-galloyl)-glucoside(2),4-hydroxy-3-methoxyphenol-1-O-β-D-(6′-O-galloyl)-glucoside(3),rutin(4),hyperoside(5),isoquercitrin(6),kaempferol-3-O-β-D-rutinoside(7),astragalin(8),myricetin-3-O-(6″-galloyl)-β-D-glucopyranoside(9),kaempferol-3-O-α-L-rhamnoside(10),di-hydromyricetin(11),astragalin-6″-O-gallate(12),myricetin-3-O-(6″-galloyl)-β-D-galactopyranoside(13),respectively.Conclusion:All compounds are isolated from Semiliquidambar cathayensis for the first time.

关 键 词：半枫荷 化学成分 黄酮 

分 类 号：R284.1[医药卫生—中药学] R284.2[医药卫生—中医学]