An Outbreak of Serogroup Y Meningococcal Meningitis in a Private Secondary Vocational School-Guangzhou City,Guangdong Province,China,2023  

作　　者：Xiang Zeng Qing He Yilan Li Yong Zhou Xiaoping Shao Pei Hu Jian Liang Yudan Song Chao Ma Lijie Zhang Limei Sun Lei Luo 

机构地区：[1]Chinese Field Epidemiology Training Program,Chinese Center for Disease Control and Prevention,Beijing,China [2]Zhuhai Center for Disease Control and Prevention,Zhuhai City,Guangdong Province,China [3]Guangdong Center for Disease Control and Prevention,Guangzhou City,Guangdong Province,China [4]Guangzhou Center for Disease Control and Prevention,Guangzhou City,Guangdong Province,China [5]Institute of Public Health,Guangzhou Medical University&Guangzhou Center for Disease Control and Prevention,Guangzhou City,Guangdong Province,China [6]Department of the National Immunization Programme,Chinese Center for Disease Control and Prevention,Beijing,China

出　　处：《China CDC weekly》2024年第12期242-246,I0005,共6页中国疾病预防控制中心周报（英文）

摘　　要：What is already known about this topic?The inclusion of meningococcal vaccines in the National Immunization Program(NIP)over several years has significantly reduced the incidence of meningococcal meningitis in China to historic lows.Worldwide,there has been a diversification of meningococcal serogroups,leading to a shift in dominant serogroups in China from serogroup A to serogroups C and B,accompanied by a rise in reports of serogroups Y and W.What is added by this report?An outbreak of serogroup Y Neisseria meningitidis(Nm)in a secondary vocational school involved a single confirmed severe case and 24 individuals with laboratory-confirmed Nm carriage.Epidemiological investigation revealed that the outbreak was localized to the classroom of the confirmed case.Prolonged close contact within a confined space was identified as a significant risk factor for Nm transmission.The genotype sequence identified was type 1655(ST-1655),which is categorized under clonal complex 23(CC-23)and bears resemblance to 8 previously confirmed cases of serogroup Y meningococcal meningitis within Guangdong Province.This suggests that serogroup Y infections continue to sporadically emerge and have become prevalent strains.What are the implications for public health practice?This outbreak underscores the critical need to enhance surveillance of meningococcal serogroups and population carrier,and advocate for vaccination with MenY-containing vaccines.

关 键 词：BREAK Secondary GUANGDONG 

分 类 号：R512.3[医药卫生—内科学]