电针联合膀胱功能锻炼治疗脊髓损伤后神经源性膀胱的系统评价及Meta分析  

Systematic Evaluation and Meta-analysis of Electroacupuncture Combined with Bladder Function Training for the Treatment of Neurogenic Bladder after Spinal Cord Injury

作　　者：杨雪 吴松梅 王茜 陈影 石淇允 YANG Xue;WU Songmei;WANG Qian;CHEN Ying;SHI Qiyun(Luoyang Orthopedic-Traumatological Hospital of Henan Province/Henan Province Orthopedic Hospital,Henan Zhengzhou 450000,China)

机构地区：[1]河南省洛阳正骨医院(河南省骨科医院),河南郑州450000

出　　处：《中国医药导刊》2024年第2期199-207,共9页Chinese Journal of Medicinal Guide

基　　金：河南省中医药科学研究专项课题(2022ZY1114)。

摘　　要：目的:通过Meta分析评价电针联合膀胱功能锻炼治疗脊髓损伤后神经源性膀胱的临床疗效。方法:系统检索The Cochrane Library、Clinical Trials、PubMed、中国知网(CNKI)、万方数据库(Wanfang Data)和维普数据库(VIP Data),按照拟定的纳入标准与排除标准进行筛选,将文献按照Cochrane协作网提供的偏倚风险项目评估手册进行质量评估,并运用Rev Man 5.3软件进行Meta分析。结果:初步检索文献535篇,按照标准最终纳入文献20篇(中文文献19篇,英文文献1篇)。结果显示,治疗有效率[OR=0.26,95%CI(0.15,0.44),P<0.00001],排尿次数[MD=-2.89,95%CI(-3.26,-2.51),P<0.00001],平均尿量[MD=65.20,95%CI(51.99,78.42),P<0.00001],最大膀胱容量[MD=44.25,95%CI(29.96,58.54),P<0.00001],最大尿流率[MD=2.08,95%CI(1.21,2.95),P<0.00001],残余尿量[MD=-31.30,95%CI(-41.41,-21.18),P<0.00001]。结论:电针联合膀胱功能锻炼有助于提高脊髓损伤后神经源性膀胱的临床疗效,但该研究尚有一定局限性,需更高质量的随机对照研究。Objective:To evaluate the clinical efficacy of electroacupuncture combined with bladder function training in the treatment of neurogenic bladder after spinal cord injury by Meta-analysis.Methods:The Cochrane Library,Clinical Trials,Database,PubMed,CNKI,Wanfang Data,and VIP Data databases were systematically searched according to the proposed literatune inclusion and exclusion criteria,and the literature was assessed for quality in accordance with the Risk of Bias Assessment Handbook provided by the Cochrane Collaboration,Meta-analysis was performed using Rev Man 5.3 software.Results:A total of 535 papers were initially retrieved,and 20 papers(19 in Chinese and 1 in English)were finally included according to the criteria.The results showed that:treatment efficacy[OR=0.26,95%CI(0.15,0.44),P<0.00001],number of urination[MD=-2.89,95%CI(-3.26,-2.51),P<0.00001],mean urine output[MD=65.20,95%CI(51.99,78.42),P<0.00001],maximum bladder capacity[MD=44.25,95%CI(29.96,58.54),P<0.00001],maximum urine flow rate[MD=2.08,95%CI(1.21,2.95),P<0.00001],residual urine volume[MD=-31.30,95%CI(-41.41,-21.18),P<0.00001].Conclusion:Electroacupuncture combined with bladder function training can help improve the clinical outcome of neurogenic bladder after spinal cord injury.However,this study has some limitations and higher quality randomized con-trolled studies are needed.

关 键 词：电针 膀胱功能锻炼 脊髓损伤 神经源性膀胱 META分析 

分 类 号：R277.5[医药卫生—中医学]