泛影葡胺造影剂对非绞窄性小肠梗阻患者行腹腔镜手术时机的判断及对术后疗效的观察  

Evaluation of operation time of laparoscopic surgery and observation of postoperative efficacy of meglumine diazotum contrast agent in patients with nonstrangulated small intestinal obstruction

作　　者：马永强 王秋红[1] 郑连生 段树全[1] 王海龙[1] 张冬胜 李小龙 韩唯杰 MA Yongqiang;WANG Qiuhong;ZHENG Liansheng;DUAN Shuquan;WANG Haiong;ZHANG Dongsheng;LI Xiaoong;HAN Weijie(Digestive Minimally Invasive Center,the Second Affiliated Hospital of Baotou Medical College,Inner Mongolia University of Science and Technology Baotou,Baotou,Inner Mongolia,014030,China)

机构地区：[1]内蒙古科技大学包头医学院第二附属医院消化微创中心,内蒙古包头014030

出　　处：《当代医学》2024年第1期32-35,共4页Contemporary Medicine

基　　金：包头市科技计划项目(2019Z3011-03)。

摘　　要：目的研究泛影葡胺造影剂对非绞窄性小肠梗阻患者行腹腔镜手术时机的判断作用及对术后疗效和血清肠脂肪酸结合蛋白(IF-ABP)、二胺氧化酶(DAO)水平的影响。方法选取2019年1月至2021年4月于内蒙古科技大学包头医学院第二附属医院消化微创中心诊断为肠梗阻的120例患者作为研究对象,按照随机数字表法分为观察组与对照组,每组60例。对照组给予胃肠减压、抗感染等基础治疗,观察组在对照组基础上行泛影葡胺造影剂下腹腔镜手术,对照组在保守治疗48h无效后行腹腔镜治疗。比较两组治疗指标、非手术治疗疗效评价指标、血清IFABP及DAO水平、术后并发症发生情况。结果观察组非手术治疗成功率高于对照组,排气时间及住院时间均短于对照组,差异有统计学意义(P<0.05)。观察组胃肠减压量少于对照组,首次肛门排便时间、症状缓解时间均短于对照组,差异有统计学意义(P<0.05)。治疗后,两组血清IFABP水平均低于治疗前,DAO水平均高于治疗前,且观察组血清IFABP、DAO水平均低于对照组,差异有统计学意义(P<0.05)。随访6个月,两组电解质紊乱、切口感染、再发肠梗阻、腹膜炎发生率比较差异无统计学意义。结论泛影葡胺造影剂对非绞窄性小肠梗阻患者行腹腔镜手术时机的判断准确,可提高非手术治疗成功率,缩短术后排便时间和住院时间,降低IFABP、DAO水平,改善患者肠黏膜缺血状态。Objective To study the effect of meglumine diatrizoate contrast agent on the operation time of laparoscopic surgery in patients with non-strangulated small intestinal obstruction and its effect on postoperative efficacy and serum intestinal fatty acid binding protein(IFABP)and di-amine oxidase(DAO)levels.Methods 120 patients diagnosed with intestinal obstruction in the Digestive Minimally Invasive Center of the Second Affiliated Hospital of Baotou Medical College,Inner Mongolia University of Science and Technology from January 2019 to April 2021 were selected as the research subjects,and they were divided into the observation group and the control group according to the random number table method,with 60 cases in each group.The control group was given basic treatment such as gastrointestinal decompression and anti-infection,the observation group was given laparoscopic surgery under meglumine diatrizoate contrast agent on the basis of the control group,the control group was given laparoscop-ic treatment after 48 h of ineffective conservative treatment,the treatment indexes,evaluation indexes of non-surgical treatment efficacy,serum IF-ABP and DAO levels,and postoperative complications were compared between the two groups.Results The success rate of non-surgical treatment in the observation group was higher than that in the control group,the exhaust time and hospitalization time were shorter than that in the control group,the differences were statistically significant(P<0.05).The gastrointestinal volume reduction in the observation group was less than that in the control group,and the time of first anal defecation and symptom relief were shorter than those in the control group,the differences were statistically significant(P<0.05).After treatment,the levels of serum IFABP of the two groups were lower than those before treatment,the levels of DAO were higher than those before treatment,and the levels of serum IFABP and DAO in the observation group were lower than those in the control group,the differences were stati

关 键 词：泛影葡胺造影 肠梗阻 腹腔镜 肠脂肪酸结合蛋白 二胺氧化酶 

分 类 号：R656.7[医药卫生—外科学]