银杏叶提取物注射液联合倍他司汀治疗脑梗死的临床效果  

Clinical effect of Ginkgo biloba extract injection combined with betahistine in the treatment of cerebral infarction

作　　者：介崇崇 JIE Chongchong(the Second People's Hospital of Zhengzhou,Zhengzhou 450000,China)

机构地区：[1]郑州市第二人民医院,河南郑州450000

出　　处：《临床医学研究与实践》2024年第11期103-106,共4页Clinical Research and Practice

摘　　要：目的分析银杏叶提取物注射液联合倍他司汀治疗脑梗死的临床效果。方法选取2022年8月至2023年8月本院收治的58例脑梗死患者为研究对象,采用电脑软件数字表抽签法将其分为对照组和研究组,各29例。对照组行倍他司汀治疗,研究组行银杏叶提取物注射液联合倍他司汀治疗。比较两组的治疗效果。结果研究组的治疗总有效率高于对照组(P<0.05)。治疗后,研究组的美国国立卫生院卒中量表(NIHSS)评分低于对照组,日常生活活动能力(ADL)、Barthel指数(BI)评分高于对照组(P<0.05)。治疗后,研究组的纤维蛋白原(FIB)、D-二聚体(D-D)水平及红细胞比容(HCT)、平均红细胞体积(MCV)均低于对照组(P<0.05)。治疗后,研究组的超氧化物歧化酶(SOD)水平高于对照组,丙二醛(MDA)水平低于对照组(P<0.05)。两组的不良反应总发生率无显著差异(P>0.05)。结论银杏叶提取物注射液联合倍他司汀治疗脑梗死效果显著。Objective To analyze the clinical effect of Ginkgo biloba extract injection combined with betahistine in the treatment of cerebral infarction.Methods A total of 58 patients with cerebral infarction admitted in our hospital from August 2022 to August 2023 were selected as the research objects.The patients were divided into control group and study group by computer software digital table lottery method,with 29 cases in each group.The control group was treated with betahistine,and the study group was treated with Ginkgo biloba extract injection combined with betahistine.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment in the study group was higher than that in the control group(P<0.05).After treatment,the National Institutes of Health Stroke Scale(NIHSS)score of the study group was lower than that of the control group,and the Activities of Daily Living(ADL)and Barthel index(BI)scores were higher than those of the control group(P<0.05).After treatment,the fibrinogen(FIB),D-dimer(D-D)levels and hematocrit(HCT),mean corpuscular volume(MCV)in the study group were lower than those in the control group(P<0.05).After treatment,the superoxide dismutase(SOD)level of the study group was higher than that of the control group,and the malonaldehyde(MDA)level was lower than that of the control group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Ginkgo biloba extract injection combined with betahistine has a significant effect in the treatment of cerebral infarction.

关 键 词：银杏叶提取物注射液 倍他司汀 脑梗死 

分 类 号：R285.5[医药卫生—中药学]