Chikungunya in Zhejiang Province,Southeast China  

作　　者：Jiangping Ren Feng Ling Ying Liu Jimin Sun 

机构地区：[1]Zhejiang Provincial Center for Disease Control and Prevention,Hangzhou 310051,China [2]Key Laboratory of Vaccine,Prevention and Control of Infectious Disease of Zhejiang Province,Hangzhou 310051,China [3]Zhejiang Provincial Station of Emerging Infectious Disease Control and Prevention,Chinese Academy of Medical Sciences,Hangzhou 310051,China

出　　处：《Infectious Medicine》2023年第4期315-323,共9页感染医学（英文）

摘　　要：Background:Chikungunya is emerging and reemerging word-widely in the past decades.It is non-endemic in Zhejiang Province,Southeast China.Aedes albopictus,one of major vectors of chikungunya,is widely-distribution in Zhejiang,and autochthonous transmission is possible after introducing chikungunya virus.Methods:Retrospectively collected the epidemiological,clinical and genetic data of chikungunya and conducted the descriptive analysis and gene sequence analysis.Results:From 2008 to 2022,29 chikungunya cases,including 26 overseas imported and 3 local cases,were reported and no cases died of chikungunya.More than half of the imported cases(53.85%)were from Southeast Asia.Seasonal peak of the imported cases was noted between August and September,and 42.31%cases onset in those 2 months.Eight prefecture-level cities and 16 counties reported cases during the study period,with Jinghua(27.59%)and Hangzhou(24.14%)reporting the largest number of cases.The 3 local cases were all reported in Qujiang,Quzhou in 2017.For imported cases,the male-female gender ratio was 2.71:1,20-30 years old cases(46.15%)and commercial service(42.31%)accounted for the highest proportion.Clinically,fever(100%),fatigue(94.44%),arthralgia(79.17%),headache(71.43%)and erythra(65.22%)were the most common reported symptoms.Eight whole-genome sequences were obtained and belonged to East/Central/South African(ECSA)or Asian genotype.Conclusions:With the change of immigration policy,the surveillance of chikungunya should be strengthened and the ability of the case discovery and diagnosis should be improved in Zhejiang in the post-COVID-19 era.

关 键 词：CHIKUNGUNYA Imported cases Epidemiological characteristics 

分 类 号：R51[医药卫生—内科学]