甲状腺全切术与次全切术治疗甲状腺多发结节的临床效果比较  

Total Thyroidectomy Versus Subtotal Thyroidectomy for Multiple Thyroid Nodules

作　　者：邵泽杰 Shao Zejie(Lanshan District Women and Children Health Center,Linyi 276000,Shandong Province,China)

机构地区：[1]临沂市兰山区妇幼保健院,山东临沂276000

出　　处：《中外医药研究》2024年第4期65-67,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:比较甲状腺全切术和次全切术治疗甲状腺多发结节的效果.方法:选取2021年5月—2023年6月于临沂市兰山区妇幼保健行手术治疗的甲状腺多发结节患者88例为研究对象,随机分成对照组和研究组,各44例.对照组行甲状腺次全切术治疗,研究组行甲状腺全切术治疗.比较两组患者的手术相关指标、术后并发症发生情况、术后创伤应激指标和甲状腺激素水平.结果:研究组手术时间、住院时间长于对照组,手术出血量少于对照组,差异有统计学意义(P<0.05).两组术后并发症发生率比较,差异无统计学意义(P>0.05).研究组复发率低于对照组,差异有统计学意义(P=0.014).术后,两组患者血钙水平均低于术前,C反应蛋白、白细胞计数水平均高于术前,差异有统计学意义(P<0.05);术前及术后1个月,两组患者血清总三碘甲状腺原氨酸、总甲状腺素、游离三碘甲状腺原氨酸、游离甲状腺素水平比较,差异无统计学意义(P>0.05).结论:甲状腺全切术和甲状腺次全切术对于治疗甲状腺多发结节均有良好的效果,而甲状腺全切术能够有效地避免复发,减少术中出血量,但手术时间与住院时间较长,临床需合理选择手术方式.Objective:To compare the effect of total thyroidectomy and subtotal thyroidectomy in the treatment of multiple thyroid nodules.Methods:88 patients with multiple thyroid nodules who underwent surgical treatment in Lanshan District Women and Children Healthcare Hospital,of Linyi from May 2021 to June 2023 were selected for the study,and were randomly divided into the control group and the study group,with 44 patients in each group.The control group was treated with subtotal thyroidectomy and the study group was treated with total thyroidectomy.The following indexes in both groups were compared:surgery-related indexes,occurrence of postoperative complications,postoperative traumatic stress indexes and thyroid hormone levels.Results:The operation time and hospitalization time of the study group were longer than that of the control group,and the surgical bleeding volume was less than that of the control group,the difference was statistically significant(P<0.05).Comparison of postoperative complication rates between the two groups showed no statistically significant difference(P>0.05).The recurrence rate of the study group was lower than that of the control group,and the difference was statistically significant(P=0.014).After the operation,the blood calcium level of both groups was lower than that before the operation,and the levels of C-reactive protein and leukocyte count were higher than that before the operation,and the difference was statistically significant(P<0.05);the levels of serum triiodothyronine,thyroid hormone,free triiodothyronine and free tetraiodothyronine were compared between the two groups before the surgery and also one month after the operation,and the difference was not statistically significant(P>0.05).Conclusion:Both total thyroidectomy and subtotal thyroidectomy have good results in the treatment of multiple thyroid nodules.Total thyroidectomy can effectively avoid recurrence and reduce intraoperative bleeding.However,the operation time and hospitalization time for total thyroidectomy are long

关 键 词：甲状腺多发结节 甲状腺全切术 甲状腺次全切术 甲状腺激素 

分 类 号：R653[医药卫生—外科学]