阻塞性睡眠呼吸暂停对男性生殖功能的影响  

Effects of obstructive sleep apnoea on male reproductive function

作　　者：王泽豪 张庆丰 杨菁[1] WANG Ze-hao;ZHANG Qing-feng;YANG Jing(Reproductive Medical Center,Renmin Hospital of Wuhan University&Hubei Clinic Research Center for Assisted Reproductive Technology&Embryonic Development,Wuhan 430060)

机构地区：[1]武汉大学人民医院生殖医学中心暨湖北省辅助生殖技术与胚胎发育临床研究中心,武汉430060

出　　处：《生殖医学杂志》2024年第4期559-562,共4页Journal of Reproductive Medicine

基　　金：国家自然科学基金项目(82101749)。

摘　　要：男性不育与环境因素、不良生活习惯、肥胖、代谢综合征以及染色体异常等密切相关,阻塞性睡眠呼吸暂停(OSA)是其中一个重要的独立危险因素。研究发现,OSA的发病率逐年上升,OSA作为男性不育的一种可逆因素,应当及时诊断并尽早进行治疗。本文就OSA与睾酮水平、勃起功能障碍(ED)、精液质量、男性不育等方面的研究进展进行综述,总结其对男性生殖功能的影响及其潜在机制。Male infertility is closely related to environmental factors,poor living habits,obesity,metabolic syndrome and chromosome abnormalities,among which obstructive sleep apnoea(OSA)is an important independent risk factor.Studies have found that the incidence of OSA is increasing year by year.As a reversible factor of male infertility,OSA should be diagnosed and treated as early as possible.This article reviews the research progress of OSA and its impact on testosterone level,erectile dysfunction,semen quality,and male infertility.It also summarizes the effects of OSA on male reproductive function and potential mechanisms.

关 键 词：男性不育症 男性生殖功能 阻塞性睡眠呼吸暂停 睡眠剥夺 间歇缺氧 

分 类 号：R711.75[医药卫生—妇产科学]