补肾活血疗法结合针刺治疗膝骨关节炎疗效及对膝关节功能、生活质量的影响  

Efficacy of therapy for tonifying kidney and activating blood combined with acupuncture on knee osteoarthritis and its influence on knee function and quality of life

作　　者：沙湖[1] 梁翼[1] 王立阳 王磊 余文景[1] SHA Hu;LIANG Yi;WANG Liyang;WANG Lei;YU Wenjing(Sichuan Provincial Orthopaedic Hospital,Chengdu 610000,Sichuan,China)

机构地区：[1]四川省骨科医院,四川成都610000

出　　处：《现代中西医结合杂志》2024年第4期485-489,共5页Modern Journal of Integrated Traditional Chinese and Western Medicine

基　　金：四川省干部保健科研课题(2020-607)。

摘　　要：目的观察补肾活血疗法结合针刺治疗膝骨关节炎的临床疗效及对患者膝关节功能、生活质量的影响。方法研究纳入2021年1月—2023年3月四川省骨科医院诊治的肾虚血瘀型膝骨关节炎患者128例,以随机数字表法分为中西医结合组与对照组各64例,对照组给予美洛昔康片、盐酸氨基葡萄糖胶囊及玻璃酸钠注射液治疗,中西医结合组在对照组治疗基础上给予补肾活血疗法及针刺治疗。2组治疗时间均为1个月,治疗过程中每组各脱落2例。比较2组患者治疗前后中医证候积分、西安大略和麦克马斯特大学骨关节炎指数可视化量表(WOMAC)评分、疼痛视觉模拟评分法(VAS)评分、生活质量健康状况调查简表(SF-36)评分、关节活动度、步速、步长,统计2组临床疗效及不良反应发生情况。结果2组患者治疗后中医证候积分、WOMAC评分、VAS评分均明显降低(P均<0.05),SF-36评分、关节活动度、步速、步长均明显增加(P均<0.05),且中西医结合组上述各指标改善情况均明显优于对照组(P均<0.05);中西医结合组治疗总有效率明显高于对照组[96.77%(60/62)比87.10%(54/62),P<0.05];2组患者不良反应发生率均较低(对照组2例,中西医结合组3例),组间比较差异无统计学意义(P>0.05)。结论补肾活血疗法结合针刺治疗膝骨关节炎临床疗效显著,可明显减轻疼痛和相关症状,改善膝关节功能,提高生活质量,且应用安全。Objective It is to observe the clinical effect of therapy for tonifying kidney and activating blood combined with acupuncture on knee osteoarthritis and its influence on knee function and quality of life.Methods A total of 128 patients with knee osteoarthritis with syndrome of kidney deficiency and blood stasis treated in Sichuan Orthopaedic Hospital from January 2021 to March 2023 were included in this study.They were divided into traditional Chinese and western medicine group and control group by random number table method,with 64 cases in each group.The control group was treated with meloxicam tablets,glucosamine hydrochloride capsules and sodium hyaluronate injection.On the basis of the treatment of the control group,the traditional Chinese and western medicine group was treated with therapy for tonifying kidney and activating blood combined with acupuncture.Both groups were treated for 1 month,and 2 cases fell off in each group during the treatment.The traditional Chinese medical syndrome scores,WOMAC scores,pain VAS scores,SF-36 scores,joint range of motion,walking speed,and step length before and after treatment were compared between the two groups,and the clinical efficacy and occurrence of adverse reactions of the two groups were calculated.Results The traditional Chinese medical syndrome scores,WOMAC scores,pain VAS scores of patients in the two groups were significantly decreased(all P<0.05),while their SF-36 scores,joint motion,walking speed and step length were significantly increased after treatment(all P<0.05),and the improvements of these indexes in the traditional Chinese and western medicine group were all significantly better than those in the control group(all P<0.05).The total effective rate of treatment in the traditional Chinese and western medicine group was significantly higher than that in the control group[96.77%(60/62)vs.87.10%(54/62),P<0.05],the incidence rates of adverse reactions in patients of the two groups were lower(2 cases in the control group and 3 cases in the traditional Chi

关 键 词：膝骨关节炎 针刺疗法 补肾活血疗法 膝关节功能 生活质量 

分 类 号：R684.3[医药卫生—骨科学]