FT3与老年缺血性心肌病伴心衰病人因心衰再入院的相关性研究  

Association of FT3 with readmissions due to heart failure in elderly patients with ischemic cardiomyopathy and heart failure

作　　者：陈珊[1] 仲崇霞 刘益海 邹任方 徐标[2] 倪杰[3] 沙杜鹃 CHEN Shan;ZHONG Chongxia;LIU Yihai;ZOU Renfang;XU Biao;NI Jie;SHA Dujuan(Department of General Medicine,Gulou Clinical Medical College,Nanjing University of Chinese Medicine,Nanjing 210008,China;Deparment of Vasculocardiology,Nanjing Drum Tower Hospital Affiliated to Nanjing University Medical School,Nanjing 210008,China;Deparment of Emergency Medicine,Nanjing Drum Tower Hospital Affiliated to Nanjing University Medical School,Nanjing 210008,China)

机构地区：[1]南京中医药大学鼓楼临床医学院全科医学科,江苏省南京市210008 [2]南京大学医学院附属鼓楼医院心血管内科,江苏省南京市210008 [3]南京大学医学院附属鼓楼医院急诊医学科,江苏省南京市210008

出　　处：《实用老年医学》2024年第4期382-385,共4页Practical Geriatrics

摘　　要：目的探讨老年缺血性心肌病伴心力衰竭(心衰)病人血清游离三碘甲状腺原氨酸(FT3)水平与病人因心衰再入院的相关性。方法选取2018年3月至2019年12月在南京大学医学院附属鼓楼医院心血管内科住院的89例老年缺血性心肌病伴心衰病人,根据此次入院是否为心衰再入院将病人分为心衰再入院组(24例)和非心衰再入院组(65例),比较2组病人住院期间的基线资料、血清学指标和超声心动图指标。采用多因素Logistic回归分析心衰再入院的相关因素。结果心衰再入院组男性比例低于非心衰再入院组,BNP、球蛋白水平高于非心衰再入院组,FT3水平低于非心衰再入院组(均P<0.05);多因素Logistic回归分析显示,校正了射血分数(EF)、左室舒张末期内径(LVEDD)、BNP、球蛋白、性别、卒中等因素后,FT3水平下降是心力衰竭再入院的独立危险因素(OR=0.198,95%CI:0.040~0.966)。结论FT3水平下降是老年缺血性心肌病伴心衰病人因心衰再入院的独立危险因素。Objective To investigate the correlation between serum level of free triiodothyronine(FT3)and readmission due to heart failure in the elderly patients with ischemic cardiomyopathy and heart failure.Methods A total of 89 elderly patients with ischemic cardiomyopathy and heart failure admitted to Department of Vasculocardiology,Nanjing Drum Tower Hospital from March 2018 to December 2019 were enrolled.According to whether the readmission was due to heart failure,the patients were divided into heart failure readmission group(group A,n=24)and non-heart failure readmission group(group B,n=65).The baseline data,serological indexes and echocardiographic indexes of the two groups were compared during hospitalization.Multivariate Logistic regression was used to analyze the related factors of readmission due to heart failure.Results The proportion of male patients in group A was lower than that in group B,the levels of BNP and globulin were higher than those in group B,and the level of FT3 was lower than that in group B(all P<0.05).Multivariate Logistic regression analysis showed that after adjusting ejection fraction(EF),left ventricular end-diastolic diameter(LVEDD),BNP,globulin,gender,stroke and other factors,decreased FT3 was an independent risk factor for readmission due to heart failure(OR=0.198,95%CI:0.040-0.966).Conclusions Decreased FT3 is an independent risk factor for readmission due to heart failure in the elderly patients with ischemic cardiomyopathy and heart failure.

关 键 词：FT3 缺血性心肌病 心力衰竭 

分 类 号：R541.6[医药卫生—心血管疾病] R542.2[医药卫生—内科学]