绝经后子宫内膜厚度早期预测子宫内膜病变的价值  

Value of endometrial thickness in early prediction of endometrial disease after menopause

作　　者：王海燕[1] 刘志强[1] 赵国芹[1] 王志敏 孟兆萍 郭庆枝[1] WANG Haiyan;LIU Zhiqiang;ZHAO Guoqin;WANG Zhimin;MENG Zhaoping;GUO Qingzhi(Department of Gynecology,Binzhou Medical University Hospital,Shandong Province,Binzhou 256500,China)

机构地区：[1]滨州医学院附属医院妇科,山东滨州256500

出　　处：《中国当代医药》2024年第9期88-91,共4页China Modern Medicine

摘　　要：目的探讨子宫内膜厚度在早期预测绝经后妇女子宫内膜病变的诊断价值。方法回顾性纳入2020年1月至2021年12月在滨州医学院附属医院妇科住院行宫腔镜检查的313例绝经后妇女为研究对象,收集患者的临床资料,根据患者阴道超声测量子宫内膜厚度是否≥5mm以及有无绝经后异常子宫出血分为三组,A组为有异常子宫出血且子宫内膜厚度≥5 mm患者102例,B组为有异常子宫出血但子宫内膜<5 mm患者53例,C组为无异常子宫出血但子宫内膜厚度≥5mm患者158例。比较三组的临床资料,同时对C组患者根据宫腔内是否发生病变进行亚组分析,观察其临床资料差异。通过ROC曲线分析子宫内膜厚度在早期预测绝经后妇女宫腔内病变的诊断价值。结果三组患者术后病理结果中占比最多的是子宫内膜息肉(48.56%),其中C组中子宫内膜息肉占比为63.29%。三组患者的子宫内膜厚度、子宫内膜病理比较,差异有统计学意义(P<0.05),A组和C组的子宫内膜厚度比较,差异无统计学意义(P>0.05),但子宫内膜病理比较,差异有统计学意义(P<0.05)。C组的亚组分析显示,子宫内膜发生病变患者的子宫内膜厚度大于子宫内膜无病变者,差异有统计学意义(P<0.05)。ROC曲线分析显示,绝经后子宫内膜厚度在早期预测宫腔内病变的AUC为0.801,敏感度为58.87%,特异度为94.12%,截断值为0.85cm。结论对于绝经后无异常子宫出血妇女通过阴道超声检查子宫内膜厚度能够对子宫内膜病变做到较好的预警,临床上可通过此方式来避免患者接受无必要有创操作,且可以提高诊断效率。Objective To investigate the diagnostic value of endometrial thickness in early prediction of endometrial disease in postmenopausal women.Methods A total of 313 postmenopausal women who underwent hysteroscopy in Binzhou Medical University Hospital from January 2020 to December 2021 were retrospectively included in the study.Clinical data of the patients were collected and divided into three groups according to whether the endometrial thickness of the patients was≥5 mm and whether there was abnormal postmenopausal uterine bleeding measured by vaginal ultrasound.Group A consisted of 102 patients with abnormal uterine bleeding and endometrial thickness≥5 mm,group B consisted of 53 patients with abnormal uterine bleeding but endometrial thickness<5 mm,and group C consisted of 158 patients with no abnormal uterine bleeding but endometrial thickness≥5 mm.The clinical data of the three groups were compared,and subgroup analysis was conducted for patients in group C according to whether intrauterine lesions occurred,and the differences in clinical data were observed.ROC curve was used to analyze the diagnostic value of endometrial thickness in early prediction of intrauterine lesions in postmenopausal women.Results Among the three groups,endometrial polyps accounted for the most(48.56%),among which 63.29%were found in group C.There were statistically significant differences in endometrial thickness and endometrial pathology among the three groups(P<0.05).There were no statistically significant differences in endometrial thickness between group A and group C(P>0.05),but there were statistically significant differences in endometrial pathology between the three groups(P<0.05).Subgroup analysis of group C showed that the endometrial thickness of patients with endometrial lesions was greater than that of those without endometrial lesions,and the difference was statistically significant(P<0.05).ROC curve analysis showed that the AUC of postmenopausal endometrial thickness in early prediction of intrauterine lesions was

关 键 词：子宫内膜厚度 绝经后妇女 子宫内膜病变 早期预测 

分 类 号：R711[医药卫生—妇产科学]