坦索罗辛在体外冲击波碎石术后的应用效果分析  

Analysis of Application Effect of Tamsulosin After Extracorporeal Shock Wave Lithotripsy

作　　者：王金录 刘辉 吕双喜 Wang Jinlu;Liu Hui;Lyu Shuangxi(Department of Urology Surgery,Beijing Daxing District Hospital of Integrated Chinese and Western Medicine,Beijing 100076,China)

机构地区：[1]北京市大兴区中西医结合医院泌尿外科,北京100076

出　　处：《中国社区医师》2024年第6期38-40,共3页Chinese Community Doctors

摘　　要：目的:分析坦索罗辛在体外冲击波碎石术后的应用效果。方法:选取2022年1月—2023年6月北京市大兴区中西医结合医院收治的输尿管结石患者156例作为研究对象,依据随机数字表法分为对照组、观察组,各78例。所有患者接受体外冲击波碎石术治疗,对照组手术后接受常规治疗,观察组在对照组基础上应用坦索罗辛治疗。比较两组治疗效果。结果:观察组术后2周排石成功率高于对照组,结石排净时间短于对照组,差异有统计学意义(P<0.05)。观察组并发症总发生率低于对照组,差异有统计学意义(P=0.031)。术后,观察组血清白细胞介素-6、C反应蛋白水平低于对照组,差异有统计学意义(P<0.05)。结论:坦索罗辛在体外冲击波碎石术后的应用有助于提高排石成功率,缩短结石排净时间,降低炎性因子水平,术后并发症发生率低。Objective:To analyze the application effect of tamsulosin after extracorporeal shock wave lithotripsy.Methods:A total of 156 patients with ureteral stones in Beijing Daxing District Hospital of Integrated Chinese and Western Medicine from January 2022 to June 2023 were selected as the study subjects.These patients were divided into control group and observation group by random number table method,with 78 cases in each group.All patients were treated with extracorporeal shock wave lithotripsy,the control group was treated with conventional treatment after surgery,and the observation group was treated with tamsulosin on the basis of the control group.The treatment effect of the two groups was compared.Results:The success rate of stone removal in the observation group was higher than that in the control group at 2 weeks after operation,the time for stone removal in the observation group was shorter than that in the control group,and the difference was statistically significant(P<0.05).The total incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant(P=0.031).After surgery,the levels of serum interleukin-6 and C-reactive protein in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).Conclusion:The application of tamsulosin after extracorporeal shock wave lithotripsy is helpful to increase the success rate of stone removal,shorten the time of stone removal,reduce the levels of inflammatory factors and the incidence of postoperative complications.

关 键 词：输尿管结石 体外冲击波碎石术 坦索罗辛 炎性因子 

分 类 号：R693.4[医药卫生—泌尿科学]