卡前列素氨丁三醇预防高危剖宫产产妇产后出血的效果及安全性评价  

Efficacy and safety evaluation of carboprost tromethamine in preventing postpartum hemorrhage in high-risk cesarean section women

作　　者：张思虎 Zhang Sihu(Department of Obstetrics and Gynecology,Jiangsu Sheyang County People's Hospital,Yancheng 224300,China)

机构地区：[1]江苏省射阳县人民医院妇产科,江苏盐城224300

出　　处：《实用妇科内分泌电子杂志》2024年第2期99-101,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探讨卡前列素氨丁三醇在高危剖宫产产妇中的应用价值及安全性。方法选取128例高危剖宫产产妇,根据随机数字表法分为对照组和研究组,各64例。采取子宫下段剖宫产,胎儿娩出后,对照组应用缩宫素干预,研究组应用卡前列素氨丁三醇干预。比较两组产妇各阶段出血量、产后出血率、红细胞计数、血红蛋白水平及不良反应发生情况。结果研究组剖宫产术后2h、24h出血量少于对照组,产后出血率1.56%低于对照组的10.94%(P<0.05)。术后2h研究组红细胞计数、血红蛋白水平高于对照组(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论高危剖宫产产妇应用卡前列素氨丁三醇能有效预防产后出血,安全性高,值得临床应用。Objective To investigate the application value and safety of carboprost tromethamine in high-risk cesarean section.Methods 128 high-risk cesarean section parturients were selected and randomly divided into a control group and a study group,with 64 cases in each group,using a random number table method.After cesarean section in the lower segment of the uterus,the fetus was delivered.The control group received intervention with oxytocin,while the study group received intervention with carboprost tromethamine.Compare the bleeding volume,postpartum bleeding rate,red blood cell count,hemoglobin level,and incidence of adverse reactions between two groups of parturients at different stages.Results The study group had less bleeding at 2 and 24 hours after cesarean section compared to the control group,and the postpartum bleeding rate was 1.56%lower than the control group's 10.94%(P<0.05).After 2 hours of surgery,the red blood cell count and hemoglobin level in the study group were higher than those in the control group(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The application of carboprost tromethamine in high-risk cesarean section can effectively prevent postpartum hemorrhage,and it is safe and worthy of clinical application.

关 键 词：卡前列素氨丁三醇 剖宫产 产后出血 安全性 

分 类 号：R714.461[医药卫生—妇产科学]